Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
  • The Effects of SEP-363856 in Healthy Volunteers with High or Low Schizotype Characteristics

    Looking for: Are you considered eccentric or consider yourself different? Do you prefer to keep to yourself? Do you believe in the supernatural or things that some people find unusual? Looking for: healthy people aged between 18 – 45 years old
    Expenses: Participants will be reimbursed for their time and travel expenses

    We are examining the effects of a single dose of a new treatment, being developed for schizophrenia, on computer tests in healthy people. If you answered yes to any of the above questions you may be able to take part in this research. To participate you must be fit and well, a light or non-smoker, right-handed and a fluent English speaker. The study involves completing an online questionnaire and visiting our research facility on 3 occasions. Please complete the online questionnaire here:

  • COMET study: understanding mood changes using iPad

    Looking for: Have you been experiencing mood swings? Have you recently engaged in risky behaviour? Have you had much more energy than usual? If so, we are looking for you!
    Expenses: Participants will be reimbursed for their time and travel expenses.

    We are investigating mood instability and cognitive function in individuals who show symptoms of mood disorders, and also individuals who have never experienced problematic moods. This study involves playing daily app-based games presented on an iPad, as well as completing 2 MRI (Magnetic Resonance Imaging) and MEG (Magnetoencephalography) brain scans during a 10-week period.

  • Bupropion Study

    Looking for: Healthy volunteers and depressed individuals required for brain scanning study
    Expenses: Participants will be reimbursed for their time and expenses

    The Department of Psychiatry are looking for both healthy volunteers and depressed individuals aged 18-50 to take part in a brain scanning study. The study compares brain activity in people who are depressed, and in people who are not depressed and investigates how an antidepressant medication (bupropion) affects information processing. The study involves two brain scans using magnetic imaging (MRI) which are completed before and after taking bupropion. Please note that healthy volunteers will NOT take the bupropion. Currently, we are particularly looking for healthy volunteers in their late 30’s and above who would be able to attend the two MRI scans at The Oxford Centre for Magnetic Resonance Imaging during normal working hours.

  • Metabolic and immune changes in people recovered from depression

    Looking for: Looking for: We are looking for people who have had at least two separate episodes of depression in the past, are now well and have been off any antidepressant medication for 6 months. You would need to be between 18 and 60 years of age and in good physical health. We are also recruiting healthy controls for this you would need to be 18-60 years, physically well and have had no history of psychological problems.
    Expenses: Participants will be reimbursed for their time and travel expenses.

    The research is helping us to understand the immune and metabolic changes that occur in depression. You would need to attend our research facility on two separate occasions during which you would complete questionnaires and a structured psychiatric interview, have a blood sample taken on one occasion, complete some computerized tasks and collect saliva samples at home for which you will be given the equipment and instructions.

  • Men needed for a brain study (COMT Study)

    Looking for: healthy men, aged 18 to 40, for a study of the effect of a gene and a drug on the performance of simple computer tasks
    Expenses: You will be reimbursed for your time.

    If you take part, we will ask you to: Provide a cheek swab (to see which form of the gene you have) then, if suitable, come to the lab and: Complete some questionnaires; Take a single tablet (either a drug or a dummy pill) and carry out simple reward tasks and tests of the processing of emotions.

  • Research into depression - you can help!

    Looking for: Are you aged 25 to 50? Are you generally healthy and able to give a blood sample? We are looking for people with Depression
    Expenses: Travel expenses will be paid.

    We would like to look at the effect that inflammation in the body may have on depression. We will look to see how people differ on tests and scans to understand more about the causes and effects of inflammation and depression.

  • Research into emotional processing – the effects of a cognitive enhancer

    Looking for: Healthy volunteers aged 18-50 years
    Expenses: You will be reimbursed for your time

    A BIT TENSE OR WORRIED? We are looking for healthy volunteers aged 18-50 years to take part in a study investigating how a single dose of the medication losartan affects learning and information processing, using simple computer tasks, EEG and MRI. Losartan is currently used to treat high blood pressure. However, we think that it may also enhance the effectiveness of psychological therapies such as Cognitive-Behaviour Therapy. The study involves two appointments of about 5 hours in total.