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Hexamethylpropyleneamine oxime (HMPAO) SPECT and 18F-FDG PET depict similar aspects of perfusion and metabolic abnormalities in Alzheimer's disease (AD), but the correspondence between them is not known in detail. We therefore used statistical parametric mapping to detect and compare abnormal brain areas objectively and quantitatively.

More information
Type

Journal article

Journal

J Nucl Med

Publication Date

01/2002

Volume

43

Pages

21 - 26

Keywords

Aged, Alzheimer Disease, Brain, Case-Control Studies, Female, Fluorodeoxyglucose F18, Humans, Male, Radiopharmaceuticals, Technetium Tc 99m Exametazime, Tomography, Emission-Computed, Tomography, Emission-Computed, Single-Photon