White matter hyperintensities in MRI scans are age related but appear to be more prevalent in depressed patients. They may be more pronounced in late onset depression. This finding, if confirmed, would potentially illuminate the heterogeneity of depression in elderly subjects.

More information
Type

Journal article

Journal

J Neurol Neurosurg Psychiatry

Publication Date

06/2008

Volume

79

Pages

619 - 624

Keywords

Age of Onset, Aged, Brain, Cerebral Ventricles, Cerebrovascular Disorders, Depressive Disorder, Depressive Disorder, Major, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Nerve Fibers, Myelinated