ApoE4 is a risk factor for the development of Alzheimer's disease, and has a functional role suggesting its importance in the neuropathology of dementia. We present a meta-analysis to investigate whether ApoE4 also affects the clinical progression of dementia in terms of cognitive decline or mortality.

More information
Type

Journal article

Journal

Int J Geriatr Psychiatry

Publication Date

05/2011

Volume

26

Pages

520 - 526

Keywords

Apolipoprotein E4, Biological Markers, Dementia, Disease Progression, Genetic Predisposition to Disease, Humans, Risk Factors