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Patients with a clinical diagnosis of Alzheimer's disease were studied using MRI, SPECT, and psychometric tests. Significant correlations between focal perfusion deficits and focal cognitive deficits were found. Significant correlations between regional relaxation time of white matter and psychometric tests of diffuse and focal categories were also found. Pathological examination confirmed Alzheimer's disease as the only diagnosis.

More information
Type

Journal article

Journal

Br J Psychiatry

Publication Date

08/1990

Volume

157

Pages

216 - 220

Keywords

Aged, Alzheimer Disease, Amphetamines, Blood Flow Velocity, Brain, Cerebral Arteries, Cerebral Cortex, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neuropsychological Tests, Organotechnetium Compounds, Oximes, Psychometrics, Regional Blood Flow, Technetium Tc 99m Exametazime, Tomography, Emission-Computed, Single-Photon