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SPECT studies were carried out on three occasions in a woman with schizophrenia. Marked 'hypofrontality' was demonstrated during an acute phase of illness. A study during remission was within normal limits, but some return of the original defect was noted in a subsequent relapse. These findings parallel those found in PET studies of schizophrenia.

Original publication

DOI

10.1192/bjp.156.3.425

Type

Journal article

Journal

Br J Psychiatry

Publication Date

03/1990

Volume

156

Pages

425 - 427

Keywords

Adult, Brain, Cerebrovascular Circulation, Chlorpromazine, Female, Flupenthixol, Humans, Schizophrenia, Temporal Lobe, Tomography, Emission-Computed, Single-Photon