Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

We studied the effects of haloperidol (0.5 mg, intravenously) on latent inhibition in an auditory paradigm and two visual paradigms in healthy subjects. Haloperidol increased latent inhibition in one visual paradigm and tended to increase latent inhibition in an auditory task, compared to saline-injected controls. These results indicate that haloperidol can enhance the selectivity of attention. In contrast, previous studies have reported that acute schizophrenics show reduced latent inhibition.

Original publication

DOI

10.1016/S0006-3223(95)00629-X

Type

Journal article

Journal

Biol Psychiatry

Publication Date

01/12/1996

Volume

40

Pages

1135 - 1143

Keywords

Acoustic Stimulation, Antipsychotic Agents, Attention, Conditioning, Operant, Double-Blind Method, Haloperidol, Humans, Injections, Intravenous, Models, Psychological, Photic Stimulation, Reaction Time, Reflex, Startle, Schizophrenic Psychology