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The SMARTbiomed Statistical Genetics Symposium is designed to bring together researchers from Denmark and Oxford who are working in the field of statistical/quantitative genetics.

Focusing on methodological advances, the event will provide an opportunity to share cutting-edge research being developed across the participating universities, while strengthening the network and collaboration among the various SMARTbiomed centres.

The symposium is open to all researchers from Oxford and Denmark. We encourage researchers to present their work and take part in this exciting moment of knowledge exchange.

 

The call for abstracts is open for both oral and poster presentations.

Please register by Wednesday 17th December

Registration Form

 

08:15–09:00

Registration & Coffee

 

 

09:00

Session 1 - Introduction by Naomi Wray

09:10–09:45

Keynote: Jian Zeng, A Bayesian method to integrate GWAS with single-cell data and its application in psychiatric disorders

09:45–10:00

Yang Luo: Improving population-scale disease prediction through multi-omics integration

10:00–10:15

 

Evan Irving-Pease, The evolutionary origins of autoimmune and infectious disease risks

10:15–10:22

 

Hannah Kockelbergh,  Defining genetic determinants of T-cell receptor repertoires at single-cell resolution

10:22–10:29

 

Jennifer Astley, Single-cell eQTL mapping identifies cell type and context-specific genetic control of disease severity

 

 

10:30-11:00

Coffee break

 

 

11:00

Session 2 — Computational statistical genetics, Chair TBD

11:00–11:35

Keynote – Pier Palamara,

11:35–11:50

Jiazheng Zhu, Leveraging ancestral recombination graphs for scalable mixed-model analyses of complex quantitative traits

11:50–12:05

Shadi Zabad, Toward whole-genome inference of polygenic scores with fast and memory-efficient algorithms

12:05-12:20

Duncan Palmer, Deviations from genetic additivity driven by rare variants at biobank scale

12:20- 12:27

Yining Fan, Scalable genealogical association testing for binary traits using ancestral recombination graphs

12:27–12:34

Peter Sørensen, Privacy-Preserving Multivariate Bayesian Regression Models for Overcoming Data Sharing Barriers in Health and Genomics

 

 

12:35–13:30

Lunch

 

 

13:30

Session 3 -  Complex Traits, Chair TBC

13:30–14:05

 

Keynote: Andrew Shork, Psychiatric Genetic Epidemiology Using Familial and Molecular Genetic Score Profiles

14:05–14:20

 

Elena Sabbioni, Estimating the Latent Dimensionality of Human Phenotypes via Factor Analysis

14:20–14:35

 

Palle Duun Rohde, Accepted Bayesian Hierarchical Modeling of Genome-wide Polygenic Signals Improves Gene Prioritization

14:35–14:42

Lianyun Huang, Estimating Genetic Correlation using Posterior Variant Effect Samples

14:42–14:49

 

Oliver Pain, Mind the Gap: Quantifying and Mitigating the Impact of Variant Missingness on Polygenic Scores

 

 

14:50-15:20

Coffee break

 

 

15:20

Session 4: Multi-ancestry, Chair TBD

15:20–15:35

Robin Walters, Adiposity, body shape, and risk of diabetes: Insights from genetic analyses in the China Kadoorie Biobank

15:35–15:50

 

Xiaotong Wang, Multi-Ancestry Conditional and Joint Analysis (Manc-COJO) applied to GWAS Summary Statistics

15:50–15:57

Yong Wang, Speeding up the genetic analysis software

15:57–16:04

 

Sarah Sarguroh, Identifying causal HLA variants that regulate protein abundance using data from two biobanks

16:05–16:40

 

Keynote: Simon Myers,

16:40

Closing Panel / Wrap-up / Networking