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Study sheds new light on how ketamine may act rapidly in the human brain
24 Sep, 2026
Researchers have identified a brain mechanism that could help explain ketamine’s unusually rapid antidepressant effects, providing new clues for the development of faster and potentially more targeted treatments for depression.
Semaglutide associated with fewer cognitive problems in people with mental illness
24 Aug, 2026
Semaglutide, widely used to treat diabetes and obesity, was associated with fewer cognitive signs and symptoms in people with psychiatric disorders, according to a new study led by researchers at the University of Oxford.
Infections linked to higher risk of brain and mental health conditions for up to two years
15 Jul, 2026
A large study of more than 1 million matched patient pairs finds that serious infections across the body are followed by increased risks of psychiatric and neurological diagnoses, especially in adults
Salsa classes shown to reduce depressive symptoms in young adults
15 Jul, 2026
A new trial led by the University of Oxford suggests it may offer a promising, accessible addition to youth wellbeing support.
Better cognition tied to higher relapse risk after depression remission
7 May, 2026
Oxford and Birmingham study with more than 3,700 UK participants challenges idea that cognitive decline would be associated with relapse risk
Declining water levels linked to air pollution and depression severity
30 Mar, 2026
New study highlights how water management and environmental change may be shaping mental health around the Great Salt Lake in Utah, USA.
Digital tool that personalises antidepressant treatment significantly improves outcomes of people with depression
4 Mar, 2026
An AI-driven tool that tailors antidepressant treatment to individual patients was shown to improve outcomes for people with depression, compared to standard treatment, in a major international trial.
New study investigates cause of repetitive negative thoughts
20 Nov, 2025
Repetitive negative thoughts will be investigated using a range of cutting-edge brain science techniques as part of a new study led by the University of Oxford and funded by Wellcome.
Shame a significant factor in hairpulling in young people, new study finds
10 Nov, 2025
It found that shame partially explained the relationship between hairpulling and depression, and fully explained the relationship between hairpulling and anxiety.
New study to investigate link between gut microbiome and emotional and cognitive wellbeing in early menopause
5 Nov, 2025
The research will add to a growing body of evidence on the effects of probiotics on mood and cognition and their ability to positively affect menopausal symptoms.
'Understanding anhedonia is very complex' - the value of lived experience
4 Nov, 2025
The GALENOS project lived experience board member Sandra Kimuge talks about working with mental health researchers on a new paper about anhedonia.
Research establishes wide variation in physical side-effects of antidepressants
22 Oct, 2025
Antidepressants differ widely in how they affect the body, according to new research from the University of Oxford and the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London.
Antidepressant withdrawal symptoms not generally that common, major new study finds
10 Jul, 2025
The largest review of antidepressant withdrawal studies to date has identified the type and incidence of symptoms experienced by people discontinuing antidepressants, finding most people do not experience severe withdrawal.
Parkinson’s drug effective in treating persistent depression
30 Jun, 2025
A drug used for Parkinson’s disease has been shown to be effective in reducing the symptoms of difficult to treat depression, in a study led by the University of Oxford.
New study finds an epilepsy drug could be effective for people with depression
1 Apr, 2025
A recent study has investigated whether ezogabine, an anticonvulsant drug given to people with epilepsy, is affective for people with depression.
Real world effects of antidepressants
30 Dec, 2024
New study compared real-world effects of different antidepressants with data from randomised controlled trials.
Radical rethink of mental health support for adolescents needed – new study
19 Dec, 2024
Young people have given important insights into what mental health support they prefer and what does not work for them or meet their needs, as part of a major new study of thousands of adolescents.
Could taking a specific anticonstipation drug reduce your risk of depression?
14 Aug, 2024
A new paper suggests that anti-constipation drug, prucalopride, may reduce the risk of experiencing depression in individuals with no past history of mental illness.
Serotonin changes how people learn and respond to negative information – new study
12 Aug, 2024
Increasing serotonin can change how people learn from negative information, as well as improving how they respond to it, according to a new study published in the leading journal Nature Communications.
Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression
5 Aug, 2024
Two pharmacological treatments used for depression affect the brain in completely different ways, shedding light on how the depressed brain gets rebalanced, according to a paper published in the journal Nature Mental Health.