Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Medically unexplained physical symptoms (MUPS) are physical symptoms which trigger the sufferer to seek healthcare, but which remain unexplained after appropriate medical assessment. They are very common, and cause significant distress and disability. Relevant aetiological factors can usually be discovered by careful and sympathetic clinical interview. What doctors say and do, and the way in which the healthcare system is organized, play a key role in aetiology. Although it is important to rule out serious physical pathology when patients present with physical symptoms, early 'positive' diagnosis of MUPS may lead to better outcomes than diagnosis by exclusion. Common psychiatric disorders, including depression, anxiety, and harmful use of alcohol, should be excluded. If reassurance and simple techniques of reattribution of symptoms do not lead to symptom resolution, cognitive-behavioural therapy (CBT) and the use of antidepressants as neuromodulating agents (rather than as antidepressants per se) can be considered. © 2008 Elsevier Ltd. All rights reserved.

Original publication

DOI

10.1016/j.mpmed.2008.06.006

Type

Journal article

Journal

Medicine

Publication Date

01/09/2008

Volume

36

Pages

449 - 451