Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS
Woods SW., Parker S., Kerr MJ., Walsh BC., Wijtenburg SA., Prunier N., Nunez AR., Buccilli K., Mourgues‐Codern C., Brummitt K., Kinney KS., Trankler C., Szacilo J., Colton B., Ali M., Haidar A., Billah T., Huynh K., Ahmed U., Adery LL., Marcy PJ., Allott K., Amminger P., Arango C., Broome MR., Cadenhead KS., Chen EYH., Choi J., Conus P., Cornblatt BA., Glenthøj LB., Horton LE., Kambeitz J., Kapur T., Keshavan MS., Koutsouleris N., Langbein K., Lavoie S., Diaz‐Caneja CM., Mathalon DH., Mittal VA., Nordentoft M., Pasternak O., Pearlson GD., Gaspar PA., Shah JL., Smesny S., Stone WS., Strauss GP., Wang J., Corcoran CM., Perkins DO., Schiffman J., Perez J., Mamah D., Ellman LM., Powers AR., Coleman MJ., Anticevic A., Fusar‐Poli P., Kane JM., Kahn RS., McGorry PD., Bearden CE., Shenton ME., Nelson B., Calkins ME., Hendricks L., Bouix S., Addington J., McGlashan TH., Yung AR.
AbstractAimTo harmonize two ascertainment and severity rating instruments commonly used for the clinical high risk syndrome for psychosis (CHR‐P): the Structured Interview for Psychosis‐risk Syndromes (SIPS) and the Comprehensive Assessment of At‐Risk Mental States (CAARMS).MethodsThe initial workshop is described in the companion report from Addington et al. After the workshop, lead experts for each instrument continued harmonizing attenuated positive symptoms and criteria for psychosis and CHR‐P through an intensive series of joint videoconferences.ResultsFull harmonization was achieved for attenuated positive symptom ratings and psychosis criteria, and modest harmonization for CHR‐P criteria. The semi‐structured interview, named Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS (PSYCHS), generates CHR‐P criteria and severity scores for both CAARMS and SIPS.ConclusionsUsing the PSYCHS for CHR‐P ascertainment, conversion determination, and attenuated positive symptom severity rating will help in comparing findings across studies and in meta‐analyses.