Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

It has been suggested that complex visual discrimination deficits in patients with medial temporal lobe (MTL) damage may be explained by damage or dysfunction beyond the MTL. We examined the resting functional networks and white matter connectivity of two amnesic patients who have consistently demonstrated discrimination impairments for complex object and/or spatial stimuli across a number of studies. Although exploratory analyses revealed some significant differences in comparison with neurologically healthy controls (more specifically in the patient with a larger MTL lesion), there were no obvious findings involving posterior occipital or posterior temporal regions, which can account entirely for their discrimination deficits. These findings converge with previous work to support the suggestion that the MTL does not subserve long-term declarative memory exclusively.

Original publication

DOI

10.1002/hipo.22056

Type

Journal article

Journal

Hippocampus

Publication Date

01/2013

Volume

23

Pages

7 - 13

Keywords

Amnesia, Diffusion Tensor Imaging, Discrimination (Psychology), Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Memory, Middle Aged, Neural Pathways, Temporal Lobe, Thalamus, Visual Perception