Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

BACKGROUND: Early childhood temperament, particularly negative emotionality (high tendency to show distress), may be a risk factor for subsequent depression. METHODS: Using data from a large UK cohort (Avon Longitudinal Study of Parents and Children), we examined the association between temperament on the Emotionality Activity Sociability Questionnaire at age 6 and ICD-10 depression at 18. Results were adjusted for a range of confounders. RESULTS: Children with high emotionality scores at age 6 had a 20% (7-36%) increase in the odds of being diagnosed with depression at age 18. CONCLUSIONS: Depression at 18 years has an early developmental diathesis, which means we may be able to identify children at risk of developing depression in young adulthood.

Original publication




Journal article


Depress Anxiety

Publication Date





729 - 736


ALSPAC, EAS, depression, emotionality, temperament, Adolescent, Child, Depression, Expressed Emotion, Female, Humans, Longitudinal Studies, Male, Shyness, Temperament, United Kingdom