Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Spine motility analysis has become the mainstay for investigating synaptic plasticity but is limited in its versatility requiring complex, non automatized instrumentations. We describe an entropy-based method for determining the spatial distribution of dendritic spines that allows successful estimation of spine motility from still images. This method has the potential to extend the applicability of spine motility analysis to ex vivo preparations.

Original publication

DOI

10.1038/srep14622

Type

Journal article

Journal

Sci Rep

Publication Date

30/09/2015

Volume

5

Keywords

Algorithms, Animals, Dendrites, Dendritic Spines, Mice, Mice, Knockout, Models, Biological, Neuronal Plasticity, Neurons