A cluster randomised trial of strategies to increase cervical screening uptake at first invitation (STRATEGIC).
Kitchener HC., Gittins M., Rivero-Arias O., Tsiachristas A., Cruickshank M., Gray A., Brabin L., Torgerson D., Crosbie EJ., Sargent A., Roberts C.
BACKGROUND: Falling participation by young women in cervical screening has been observed at a time that has seen an increase in the incidence of cervical cancer in the UK in women aged 90%. CONCLUSION: Women receiving their initial screening invitation frequently delay taking up the offer and the net impact of interventions was small. Timed appointments and SSKs sent to non-attenders at 6 months are likely to be a cost-effective means of increasing uptake and should be considered further. HPV vaccination in the catch-up programme was associated with an increased uptake of cervical screening. Future work should focus on optimising self-sampling in terms of age range, timing of offer for non-attenders and use of urine testing instead of vaginal samples. TRIAL REGISTRATION: Current Controlled Trials ISRCTN52303479. FUNDING: This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 68. See the NIHR Journals Library website for further project information.