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Cellular homeostasis, maintenance of the balance of life and death at the cellular level is essential for tissue integrity from development through senescence. During development of the nervous system programmed cell death is responsible for establishing the number of neurons and shaping of the nervous system.

Type

Chapter

Book title

Neurochemical Mechanisms in Disease: Advances in Neurobiology. Handbook of Neurochemistry

Publisher

springer

Publication Date

2011

Volume

1

Pages

17 - 39

Addresses

Dr. Carol M. Troy, Columbia University Medical Center, pathology, neurology and Taub Center for the Study of the Alzheimer's Disease and the Aging Brain, 168st, New York, New York, 10032, United States

Keywords

Neuron death, Caspase, IAP, Smac/DIABLO, TNF, Fas, PIDD, RAIDD, Neurodegenerative Disease