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A role for APP in Wnt signalling links synapse loss with β-amyloid production.

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Elliott C. et al, (2018), Transl Psychiatry, 8

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil.

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Sellers KJ. et al, (2018), Alzheimers Dement, 14, 306 - 317

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons.

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Robbins JP. et al, (2018), Front Neurosci, 12

Insulin signalling in Alzheimer's disease and diabetes: from epidemiology to molecular links.

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Ribe EM. and Lovestone S., (2016), J Intern Med, 280, 430 - 442

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.

Journal article

Killick R. et al, (2014), Mol Psychiatry, 19, 88 - 98

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

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Jean YY. et al, (2013), Biochem J, 455, 15 - 25

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD.

Journal article

Ribe EM. et al, (2012), Biochem J, 444, 591 - 599

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

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Ribe EM. et al, (2012), BIOCHEMICAL JOURNAL, 444, 591 - 599

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory.

Journal article

Puzzo D. et al, (2011), Ann Neurol, 69, 819 - 830

Molecular Mechanisms of Neuronal Death


Ribe Garrido EM. et al, (2011), Neurochemical Mechanisms in Disease: Advances in Neurobiology. Handbook of Neurochemistry, 1, 17 - 39

Cystatin C protects neuronal cells from amyloid-beta-induced toxicity.

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Tizon B. et al, (2010), J Alzheimers Dis, 19, 885 - 894

Mechanisms of neuronal death in disease: defining the models and the players.

Journal article

Ribe EM. et al, (2008), Biochem J, 415, 165 - 182

Caspase-2: vestigial remnant or master regulator?

Journal article

Troy CM. and Ribe EM., (2008), Sci Signal, 1

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

Journal article

Nieto M. et al, (2006), Neurobiol Aging, 27, 848 - 856

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