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We have been awarded an extra ACL (ST4) post from NIHR, with the recruitment window opening in April 2015.

1. Description and strengths of the specialty specific programme; please highlight research track record including any markers of esteem:

Since the establishment of the Oxford Foundation Chair in Old Age Psychiatry (Ebmeier, 2006), we have attracted £8m research funding for Old Age Psychiatry (including £2.5m for the cognitive ageing theme as part of the Oxford Biomedical Research Centre). Our research group has generated well over 200 papers, books and chapters. We were joined this month by Professor Simon Lovestone (Professor of Translational Neuroscience) from the Institute of Psychiatry (King’s College London), who will add to the scientific supervision of trainees, especially in the –omics of dementia and in the study of large clinical data sets. We have trained 3 ACFs: one was selected “Royal College of Psychiatry Core Trainee of the Year 2011”, as well as being awarded a 2011 International Psychogeriatric Association (IPA) Junior Research Award and a Wolfson Junior Research Fellowship. Two have secured funding from the Oxford Health Service Research Fund for his independent research project. Since 2007, we have trained 7 PhD students and 1 MD (4 completed). In Aug 2013 two new ACFs have joined our team, one specifically appointed for run-through into old age psychiatry after national competition, the other ACF is post-doc. We have appointed to a matched MRC–funded CL post in 2012. A further ACL in Old Age Psychiatry, allocated after National Competition, has been appointed in 2013.

2. Description of the research component of the specialty specific programme:

Ebmeier is co-grant holder of the MRC grant for Phase 12 of the Whitehall II Cohort based at UCL (2013-17). An imaging study funded in 2012 through “Lifelong Health & Wellbeing” by the MRC, combines information from Phase 11 of the Whitehall II study with detailed structural and functional MRI data in 800 randomly selected participants to examine the effects of biological, social and psychological risk factors on brain and mental health. As the members of the cohort are now 50-85 years old, the main focus of the study has become the aetiology of dementia, as well as the investigation of protective factors examined longitudinally over the past 25 years. Furthermore, 500 blood samples and mucosal swabs are taken to examine proteomics, transcriptomics, metabolomics and microbiome analysis, gene expression profiling (DNA microarrays & high throughput DNA sequencing),  in vitro cellular models (activation & regulation of cytokine networks plus host­microbe interactions), and advanced  bioinformatics tools and systems biology methods to characterise immune state in participants. In addition, we examine the effects of exercise and psychological stimulation on mechanisms of brain plasticity that may increase resilience against cognitive ageing (Oxford BRC with Johansen-Berg & Nobre). Close links exist within OxDARe (Oxford Dementia and Ageing Research) and the Oxford Parkinson's Disease Centre (OPDC).

3. Description of the clinical component of the specialty specific programme:

The general adult and old age psychiatry advanced training programme supports training for 25 whole time equivalent advanced trainees – with a larger number of approved posts to select from. Clinical placements in Oxford Health and Berkshire NHS Foundation Trusts are rated highly in the GMC trainee survey, particularly for its year-long clinical and more continuous educational supervision.  There are ten posts with advanced old age psychiatry trainers that trainees may choose.  Dementia care is integrated across all NHS trusts in the area, with common triage and joint recruitment into studies from memory clinics via DeNDRoN. CL clinical training will occupy 50% of the total time with the remainder dedicated to research. This will be offered in the most appropriate way for the trainee’s research, en bloc or as regular time away from clinical duties.

4. Description of how the post complements the proposed 2015 specialty spread for the posts allocated by formula:

This post is complementary to the above MRC-funded clinical lecturer. It will also be synergistic and complementary to other CLs appointed to Neurology, Psychiatry or General Practice.

5. Suitability of the Institution to host posts within this specialty:

The establishment of the Foundation Chair together with the attraction of a second chair in Translational Neuroscience of dementia has created an ideal setting for higher academic psychiatric training in Oxford, based on strong and well-supported research programmes that can easily accommodate the infrastructure needs of an additional ACL.

6. Description of any innovative / interdisciplinary / new research approaches in this area:

Old age psychiatry research in Oxford is supported by a world-class imaging infrastructure, providing 1.5, 3 (2x) and 7 Tesla research-dedicated scanners, PET-CT, as well as magneto-encephalography. Linkup to epidemiological data sets (Whitehall II; OPTIMA), to strong psycho- and neurophysiological teams, to the Oxford Clinical Trials Unit for Mental Illness, and to the Clinical Neurosciences Groups of the Oxford BRC, offers opportunities for interdisciplinary initiatives and training. A research programme embedded in the Oxford BRC has recently acknowledged our innovative interdisciplinary approach.

Key staff involved:

  1. Academic Lead (University) for the IAT Programme: Professor C.W. Pugh, Director of OUCAGS and Professor of Renal Medicine, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN
  2. Academic Supervisor (University): Professor K P Ebmeier, Foundation Professor of Old Age Psychiatry (University of Oxford), University Department, Warneford Hospital, Oxford OX3 7JX, Telephone: 01865 226469, Email: klaus.ebmeier@psych.ox.ac.uk
  3. Education Supervisor (Trust) Details: Will be appointed for the duration of the Clinical Lecturer’s tenure in the Programme by TPD from list of 10 Psychiatrists of Old Age. All are approved Educational Supervisors of the Oxford School of Psychiatry.
  4. Clinical Supervisor(s) Details: Will be appointed for each year of Clinical Placement in consultation with the Academic Supervisor, Programme TPD and Clinical Lecturer from the list of 10 Psychiatrists of Old Age. All are approved Clinical Supervisors of the Oxford School of Psychiatry.
  5. LETB Training Programme Director Details: Dr Susan Shaw  Consultant Psychiatrist and Honorary Senior Clinical Lecturer, Lead TPD for GA/OA Advanced Trainees, Oxford Health NHS Foundation Trust, City Central CMHT, Mental Health Division, Warneford Hospital,