Oxford Cognitive Approaches to Psychosis
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Founded in 2011
22 team members
Over 800 citations of our paranoia model paper
We investigate why people experience hallucinations and delusions, and use that knowledge to develop truly effective treatments for these problems. Our targeted interventions for paranoia are now being tested in randomized controlled clinical trials.
Our research has shown that hallucinations and delusions are far more common than previously believed. Indeed many people in the general population will have experienced them in a relatively mild form. For others, however, these experiences can cause real distress. We work to understand why they happen and how they can be treated.
Mental health problems are complex phenomena. To help us explain how hallucinations and delusions are caused and why they can persist, we follow best practice and focus on particular experiences – for example, feelings of paranoia. Drawing on a variety of approaches, including epidemiological studies, psychological experiments, clinical trials, and a ground-breaking virtual reality laboratory, we use our theoretical knowledge to develop carefully tested treatments that will truly make a difference.
Alongside these clinical interventions, we are committed to making our research - and especially therapeutic techniques - available to the widest possible audience, with several books for the general reader published and more in preparation. Our work is supported by the NHS National Institute of Health Research, Medical Research Council, and the Wellcome Trust.
Recent open access papers
- Treatable clinical intervention targets for patients with schizophrenia
- Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange)
- The weeks before 100 persecutory delusions: the presence of many potential contributory causal factors
- Suicidal ideation and behaviour in patients with persecutory delusions: Prevalence, symptom associations, and psychological correlates
- The comments of voices on the appearance of patients with psychosis: ‘the voices tell me that I am ugly’
- Automated psychological therapy using immersive virtual reality for treatment of fear of heights: a single-blind, parallel-group, randomised controlled trial
- The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis
- Disrupting sleep: the effects of sleep loss on psychotic experiences tested in an experimental study with mediation analysis
- Virtual reality in the assessment, understanding, and treatment of mental health disorders
- Persecutory delusions: a cognitive perspective on understanding and treatment [pdf]
- Virtual reality in the treatment of persecutory delusions: randomised controlled experimental study testing how to reduce delusional conviction
- The concomitants of conspiracy concerns
- Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot trial
- Effects of cognitive behaviour therapy for worry on persecutory delusions in patients with psychosis (WIT): a parallel, single-blind, randomised controlled trial with a mediation analysis
- Targeting Recovery in Persistent Persecutory Delusions
- The role of sleep dysfunction in the occurrence of delusions and hallucinations: a systematic review
- Advances in understanding and treating persecutory delusions: a review
- An early Phase II randomised controlled trial testing the effect on persecutory delusions of using CBT to reduce negative cognitions about the self: The potential benefits of enhancing self confidence
- Height, social comparison, and paranoia: An immersive virtual reality experimental study
- Discussion of "Height, social comparison, and paranoia: An immersive virtual reality experimental study": Video 1
- Paranoia and post-traumatic stress disorder in the months after a physical assault: a longitudinal study examining shared and differential predictors
- How cannabis causes paranoia: Using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to paranoia
Funded by the Medical Research Council.