LGI1-antibody encephalitis: how to approach this highly treatable dementia mimic in memory and mental health services.

Binks SNM., Al-Diwani A., Handel AE., Bajorek T., Manohar S., Husain M., Irani SR., Koychev I.

Leucine-rich glioma-inactivated 1-antibody-encephalitis is a treatable and potentially reversible cause of cognitive and psychiatric presentations, and may mimic cognitive decline, rapidly progressive dementia and complex psychosis in older patients. This aetiology is of immediate relevance given the alternative treatment pathway required, compared with other conditions presenting with cognitive deficits.

DOI

10.1192/bjp.2024.72

Type

Journal article

Publication Date

2024-06-01T00:00:00+00:00

Volume

224

Pages

252 - 257

Total pages

5

Keywords

Dementia, leucine-rich glioma-inactivated 1, neuroimmunology, older adults, psychosis, Humans, Dementia, Autoantibodies, Encephalitis, Intracellular Signaling Peptides and Proteins, Diagnosis, Differential, Aged, Mental Health Services, Female, Male

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