Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
True True

Recent Publications

5 View 31 more »

Ann Sharpley

BSc, PhD


Trials Manager & Polysomnographer

Research Summary

My research focuses on the psychopharmacology of mood disorders (depression and bipolar disorder) with a particular interest on the effects of drugs on sleep.

I am part of Professor Phil Cowen's Psychopharmacology Research Group and work closely with Dr Beata Godlewska and Clare Williams on studies using magnetic reesonance spectroscopy (MRS) to measure brain chemicals, particularly glutamate, in people with depression and those undergoing interferon treatment for hepatitis C.

For many years the main focus of my research has been the use of ambulatory technology (polysomnography and actigraphy) to measure the effects of drugs on sleep in volunteers and patients. Currently, working with Dr Nisha Singh, we are looking at the effects of ebselen, a lithium like compound on sleep and MRS.

I am experienced in managing clinical trials, for example PRE-EMPT and MIAMI-UK.

True True

Recent Publications

5 View 31 more »