Personalized home based neurostimulation via AI optimization augments sustained attention.

Cohen Kadosh R., Ciobotaru D., Karstens MI., Nguyen V.

Brain-based technologies for human augmentation face challenges in personalization and real-world translation. We present an AI-driven personalized Bayesian optimization algorithm that remotely adjusts neurostimulation parameters based on baseline ability and head anatomy to enhance sustained attention at home. Validated through in silico modeling and a double-blind, sham-controlled study, our approach aligns with MRI-based models and neurobiological theories, maximizing efficacy and enabling scalable, personalized cognitive enhancement and therapy in real-world settings.

DOI

10.1038/s41746-025-01744-6

Type

Journal article

Publication Date

2025-07-29T00:00:00+00:00

Volume

8

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