James Griffiths

Clinical Trials Manager

My role as part of the Oxford Brain Health Clinical Trials Unit is to support the set-up and delivery of clinical trials. Currently I am managing the NIHR EME funded PAX-D trial in treatment resistant depression, led by Dr Michael Browning.

Prior to joining the OBHCTU and the Department of Psychiatry in 2019, I worked on a variety of clinical trials in paediatric and adult haemato-oncology, neonatal intensive care and acute brain injury in the NHS, at the University of Oxford's NPEU CTU and then the CR UK & UCL Cancer Trials Centre, as a Trial Manager and then Senior Trial Manager.

Recent publications

PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.
Journal article

Au-Yeung SK. et al, (2021), Evid Based Ment Health
Women in science: achievements and ambitions
Journal article

Delanerolle G. et al, (2021), British Journal of Neuroscience Nursing, 17, 13 - 16
Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial.
Journal article

ELFIN trial investigators group None., (2019), Lancet, 393, 423 - 433
Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT.
Journal article

Griffiths J. et al, (2018), Health Technol Assess, 22, 1 - 60
Summary Protocol for a Multi-Centre Randomised Controlled Trial of Enteral Lactoferrin Supplementation in Newborn Very Preterm Infants (ELFIN).
Journal article

The ELFIN Trial Investigators Group None., (2018), Neonatology, 114, 142 - 148
Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial.
Journal article

Azzopardi D. et al, (2016), Lancet Neurol, 15, 145 - 153
Anticonvulsant effect of xenon on neonatal asphyxial seizures.
Journal article

Azzopardi D. et al, (2013), Arch Dis Child Fetal Neonatal Ed, 98, F437 - F439
Comparing the function of the corticospinal system in different species: organizational differences for motor specialization?
Journal article

Lemon RN. and Griffiths J., (2005), Muscle Nerve, 32, 261 - 279

More publications