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- Neural Correlates of Gene Function Research Group
Kristian Reveles Jensen
MD MSc (res)
I am conducting an MSc under the co-supervision of Elizabeth Tunbridge, in the Department of Psychiatry, and Mark Walton, in the Department of Experimental Psychology.
My research focuses on a common mutation in the dopamine system (the COMT Val158Met polymorphism) and its effect on learning and behaviour. I use a sequential action and decision task a transgenic animal model of COMT and pharmacological and environmental interventions combined with computer modelling to study the interaction between COMT, dopamine, stress and learning.
I have a BSc in Biotechnology and am a final year medical student from the University of Copenhagen, where I also teach human neuroanatomy. I have a great interest in both the clinical, scientific and philosophical aspect of the brain and mind. When I worked as a locum in neurology and psychiatry, I commuted continuously between the clinic and the lab.
My previous work has been using CLARITY for lipid removal to enable large volume staining and confocal microscopy for investigation of the architecture of the nervous system. Latest with electrophysiologist Rune Berg to find fixable lipophilic dyes to trace electrode placement and neuronal projections. Other projects have ranged from developing neuronal assays to studying viral entry mechanisms into the brain.
My work is funded by The Medical Society in Copenhagen, The Augustinus Foundation, The Oticon Foundation and The Department of Psychiatry, Oxford University.
Jensen KHR. and Berg RW., (2016), Scientific Reports, 6
Petersen PC. et al, (2014), Journal of Neuroscience, 34, 2774 - 2784