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Neuropsychological impairment is a key feature of late-life depression, with deficits observed across multiple domains. However, it is unclear whether deficits in multiple domains represent relatively independent processes with specific neural correlates or whether they can be explained by cognitive deficits in executive function or processing speed.

More information

Journal article


Psychol Med

Publication Date





1195 - 1202


Age Factors, Aged, Anisotropy, Brain, Brain Mapping, Case-Control Studies, Cognition Disorders, Depressive Disorder, Executive Function, Female, Humans, Magnetic Resonance Imaging, Male, Memory, Episodic, Middle Aged, Neuropsychological Tests, Neuropsychology, Reaction Time, Severity of Illness Index