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  • Are you interested in how the brain works? Men needed!

    If you take part, we will ask you to: - Provide a cheek swab (to see which form of the gene you have) then, if suitable, come to the lab and: - Take a single dose of a drug or a dummy pill; - Fill in some questionnaires and give samples of saliva; - Complete tasks of mental maths, memory and reward, while in an MRI brain scanner. The study will take one afternoon (around 3.5 hours).

  • Lamotrigine and Brain Imaging Study: Healthy Volunteers Needed

    This project is about studying the effects of a single dose of oral lamotrigine, a commonly prescribed medication for epilepsy and bipolar depression, on brain activity using brain imaging technology. The study would involve 2 visits lasting approximately 1 and 5 hours, respectively. Ethics Approval Reference: R49749/RE001

  • Can brief daily mental exercises change the way the human brain processes certain kinds of information?

    The aim of this study is to investigate the effects of certain brief mental exercises on the way in which the brain processes specific kinds of information. We are looking for healthy participants (both male and female), aged 18 to 65 years. In order to participate, you must be in good health, not be regularly engaged in any kind of formal mental exercises (e.g. yoga, meditation, mindfulness practices, positive psychology exercises, psychotherapy etc.) and you must not have a history of any mental disorder (such as depression, anxiety disorder, or eating disorder). You would be invited to the Department of Psychiatry (Warneford Hospital) for two study sessions. Both sessions would take approximately 60 to 90 minutes. Between the sessions you would be assigned a brief mental exercise (taking approximately 10 minutes per day) and you would be asked to carry out this exercise each evening for 7 days. After practising for 7 days, your performance on a range of computerized psychological tasks would be assessed. If you are interested and would like more information, please contact Dr Alexander Kaltenboeck (alexander.kaltenboeck@psych.ox.ac.uk) at the Department of Psychiatry. Ethics Approval Reference: R49254/RE003

  • Eating Concerns and Compulsivity

    We are currently looking for people that fit into one of two: healthy people who have been recovered from anorexia nervosa for over a year, and those who think a lot about their eating, weight and shape. You should be a healthy female aged between 18 and 45 years. We are looking for women who do not have any current health or psychiatric problems. We will be asking you to do some questionnaires and complete two computer tasks, which measure behaviour thought to be related to compulsivity. Compulsivity is repetitively performing actions which aren’t rewarding or good for you. We will also non-invasively measure your pupils during one of the tasks.

  • Participants needed for emotional processing drug study- Ethics Ref: R50651/RE001

    The study mainly involves computer-based psychological tasks on emotional and cognitive processing and the taking of blood samples.

  • OxCaMS

    Have you been experiencing mood swings? Have you recently engaged in risky behaviour, been so hyper that you got into trouble, had much more energy than usual and/or been so irritable that you started fights?

  • The effect of losartan on fear learning

    We are looking for healthy volunteers aged 18-40 years and fluent in English to take part in a study investigating how a single dose of the medication losartan affects learning and information processing, using a simple computer task. Losartan is currently used to treat high blood pressure. However, we think that it may also enhance the effectiveness of psychological therapies such as Cognitive-Behaviour Therapy. The study involves three appointments of about 5 hours in total.

  • Ebselen as an add-on treatment in hypo/mania

    Lithium can stabilise the highs and lows of mood but requires careful monitoring. We are interested in a new lithium-like medicine called ebselen which might help improve recovery from acute hypo/manic episodes. The study involves adding ebselen to your usual medication during an acute episode of hypo/mania.

  • How does your problem solving ability relate to measures of heart rate and hormonal function?

    Healthy male volunteers aged 18-40 years are needed for a study investigating the relationship between abilities on computerized problem solving tasks and measures of heart rate, skin sweating, and hormonal function. Central University Research Ethics Committee number: R53870/RE001

  • How women with and without eating disorders perceive bodies

    The study involves one session, 1.5-2 hours long, at the Department of Psychiatry at the Warneford Hospital site in Headington. You would complete a structured interview to see whether you have an eating disorder, and some computer tasks relating to how you see and feel about your own and others’ bodies. The study also involves being weighed and having your height measured – it will be up to you whether you are told your weight and height or not.

  • Are spiders a problem for you?

    We are looking for healthy volunteers aged 18-60 years and fluent in English to take part in a study investigating how a single dose of the medication hydrocortisone affects attention for spiders, using simple computer tasks. Hydrocortisone is a stress hormone also naturally occurring in the body. However, we think that it may also enhance the effectiveness of psychological therapies such as Cognitive-Behaviour Therapy. The study involves four appointments of about 5 hours in total.

  • Volunteers Needed for Learning Study

    We are looking for healthy volunteers aged between 18 to 65 to improve our understanding of how people learn which are the best choices to make in day-to-day living. The study will take about 2 hours of your time and will take place in the Department of Psychiatry at the Warneford Hospital. During the study you would be asked to complete some simple tasks while an eye tracker device measures the changes in your pupil size.

  • Volunteers needed for a study investigating the effects of mental exercises

    You would be invited to the Department of Psychiatry (Warneford Hospital) for two study sessions. Both sessions would take approximately 60 to 90 minutes. Between the sessions you would be assigned a brief mental exercise (taking approximately 10 minutes per day) that you carry out for 7 days. After this training period, your performance on a range of computerized psychological tasks will be assessed.

  • Brain Stimulation Study

    We are looking for healthy volunteers to improve our understanding of how the brain is organised and how it processes information during motor learning. Transcranial Direct Current Stimulation (TDCS) is a form of neurostimulation that uses constant, low current delivered to the brain area of interest via sensors on the scalp. Participants may experience some discomfort during TDCS. This study involves two visits to the Department of Psychiatry in Oxford. Each session will take around two hours of your time.

  • Neural mechanisms underlying decision making

    Who are we looking for? Healthy fluent English-speaking people aged 18-85 who are not pregnant. You will be asked questions about your medical history to check your suitability for an MRI scan. MRI is a method to measure brain activity that allows us to see how the brain is organised, processes information and performs skills like speech or memory. This scan is safe and does not involve any needles or injections.

  • VOLUNTEERS NEEDED FOR ONE-TO-ONE INTERVIEW ON BRAIN HEALTH

    We are conducting a research study to investigate people’s perceptions of the brain and brain health (Ethics Approval Reference: R56033/RE001). The study is led by the EU-funded Lifebrain consortium (www.lifebrain.uio.no).

  • Friends of Oxford Dementia and Ageing Research (OxDARE)

    Anyone who is interested in finding out more about dementia and ageing research in Oxford is invited to become a Friend of OxDARE. Friends can choose to register an interest in taking part in future studies and/or receive quarterly newsletters. When new studies get underway, OxDARE researchers will invite interested Friends to take part by email. If you are contacted by one of our researchers, it is your choice whether you would like to participate in their study or not.

  • Volunteers needed for Dementia Prevention Study: European Prevention of Alzheimer’s Dementia (EPAD)

    The European Prevention of Alzheimer’s Dementia (EPAD study) aims to address the urgent need for new treatments designed to prevent Alzheimer’s Dementia. The main study objectives are to: 1. Learn and understand better the factors involved in developing Alzheimer’s dementia. 2. To develop new treatments more quickly which are hoped to prevent Alzheimer’s dementia.

  • Dynamics of perceptual decision making

    During this study you will learn and perform a task that involves judging the direction of motion of clouds of moving dots. You will participate in a maximum of 4 sessions; first you will learn how to do the task on a computer. Then you will do 1-2 sessions performing the task while we record your brain activity using magnetoencephalography (MEG). MEG is a safe neuro-imaging technique that records the weak magnetic fields produced by the synchronised firing of neurons in the brain. MEG sessions will last up to 2 hours. Finally, we will make a 3D image of your brain using magnetic resonance imaging (MRI) which we will use to localise the neural generators of the MEG signals.