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Virtual reality game with pain stimulation and EEG monitoring

Looking for: 18-60 years old healthy volunteers
Expenses: Participants will be reimbursed for their time

Are you healthy and between 18-60 years old? Then we invite you to participate in our research which will take about one hour. During your visit, we will measure your body movements, physiological signals, and your subjective pain ratings while you play a virtual reality game in which brief electrical pain stimuli will be administered. You will be compensated for your time. If you are interested or if you want more information about the study, please contact: Pranav Mahajan (pranav.mahajan@linacre.ox.ac.uk) or Shuangyi Tong (shuangyi.tong@eng.ox.ac.uk) Ethics Committee Reference: R58778/RE002

Imaging the brain's response to faces

Looking for: If you are healthy, fluent English-speaking, not pregnant and aged between 18 and 40 years, we invite you to take part.
Expenses: Participants will be reimbursed for their time and reasonable travel expenses

If you are healthy, fluent in English-speaking, not pregnant, and aged between 18 and 40 years, we invite you to take part in a study to image the brain’s response to faces using the 7T MRI scanner. If you take part, we will ask you to: • Answer some questions over the phone to confirm eligibility. You will also be asked questions about your medical history to check your suitability for an MRI scan. • Complete simple tasks whilst having a brain scan in a 7T MRI scanner MRI scanning allows us to see how the brain is organised, processes information, and performs skills like speech or memory. This scan is safe and does not involve any needles or injections. We will follow all COVID-19 safety guidelines The study takes place at the Oxford Centre for Functional MRI of the Brain (FMRIB), located at the John Radcliff Hospital, and will take up to 2 hours in total for which you will be reimbursed together with your travel expenses. Interested? Please contact Dr. Marieke Martens amygdala.study@psych.ox.ac.uk for further information without any obligation. Department of Psychiatry CUREC Ref: R74004/RE001

Are you interested in participating in a brain scan study?

Looking for: We are looking for participants aged between 18-70 years old to match the patient group.
Expenses: Time and travel expenses will be reimbursed.

We are looking for people without any history of mental illness and currently not taking any medication. This can help us to explore the differences between healthy and depressed individuals. The study involves having a single brain scan using magnetic imaging (MRS) and computerised tasks. Should you like to get involved please contact Fitri Fareez Raml at fitri.ramli@psych.ox.ac.uk or ebselen@psych.ox.ac.uk. More information about our research can be found on the link provided. The study has been approved by the University of Oxford Central University Research Ethics Committee Reference: 20/SC/0151

How clinicians use the output of Artificial Intelligence tools to inform their decision making

Looking for: Medical students (any year) and qualified medical doctor volunteers (any specialty, any career grade) who are aged 18 and over, to participate in an online study to investigate the above aims. You are invited to complete a short survey for one session, taking approximately 20-30 minutes.
Expenses: Participants are not reimbursed for their time.

Clinical decision support tools (CDSTs) take an input – i.e. data about a patient – and deliver an output in the form of a decision, recommendation or prediction. This output is presented alongside a certainty estimate – i.e. how certain or uncertain the tool is about its prediction. In order to utilise CDSTs in practice, clinicians will be required to interpret both the output of a tool, and its uncertainty estimate, and integrate this with their own clinical assessment. The aim of this study is to understand how medically trained individuals interpret and process the output of artificial intelligence clinical decision support tools. The study has been approved by University of Oxford Central University Research Ethics Committee Reference: R80680/RE001

Reward, Emotion, Learning and Ketamine Study (RELAKS) Study.

Looking for: Healthy Volunteers aged 18 and above.
Expenses: You will be compensated for your time.

Volunteers needed for magnetic resonance study of the brain in response to Ketamine. MRI is a type of brain scan that allows us to see how the brain is organised and performs tasks like decision making. The scan is safe and does not involve any needles or injections. A licensed drug called ketamine affects the levels of glutamate, a chemical messenger in the brain. Glutamate plays a role in learning and memory so we are interested in understanding how ketamine can affect these. We are looking for volunteers to improve our understanding on how ketamine can influence the way people learn from rewards and punishments. The study involves 1 phone screening interview and 4 in-person visits (3 times to Warneford hospital, one time to John Radcliffe Hospital) over 2-3 weeks, each lasting up to 2-3 hours. In all, your participation will involve: medical and psychiatric health screening (including blood and urine tests and providing saliva samples to measure a stress hormone), drug administration, questionnaires and computer tasks and an MRI scan, that will involve administering electrical pain which will be calibrated to your personal pain threshold. Who are we looking for? Fluent English-speaking men or women aged between 18-45 years, who do not suffer from any psychiatric conditions, who are not using any psychotropic medication and are not pregnant. You will be asked questions about your medical history to check your suitability to participate in the study. If you are interested and would like more information please contact Reward, Emotion, Learning and Ketamine Study (RELAKS) Study team at the Department of Psychiatry, Warneford Hospital, Oxford on relaks@psych.ox.ac.uk.

The Oxford Institute of Clinical Psychology Training and Research

Looking for: First Time Mums needed.
Expenses: Questionnaire

Are you a UK-based Mum? Is your baby under 10 weeks old? Please consider taking part in this online questionnaire study about stress, anxiety and social support after giving birth. It is hoped that this research will help us better understand how to support new Mums during such an important and precious time in your child’s life. Please follow the link below to take part https://psychiatryoxford.qualtrics.com/jfe/form/SV_37YBWx0ayaIhNnD OR contact joanna.maher@hmc.ox.ac.uk for more details

Are you experiencing depression despite taking antidepressants?

Looking for: Participants to take part in a study investigating how a new anti-inflammatory drug affects emotional and rewarding information in depression.
Expenses: You will be reimbursed for your time!

Duration: Three appointments (one screening visit, two research visits) about 8 hours in total Who can participate? People who feel depressed despite antidepressant treatment, aged 18 to 65 What does the study involve? Psychological tasks, one brain scan using functional Magnetic Resonance Imaging (fMRI), and taking medication for 7 days.

Healthy volunteers needed for a drug study investigating how a commonly-used antidepressant influences how people process emotional information about themselves and others.

Looking for: Healthy Volunteers aged 18-45 years
Expenses: You will be compensated for your time

We will ask you to attend two sessions for approximately 7 hours in total. In the first session we will ask you some questions about your current health and medical history to check your suitability for the study. If you are female, we will also ask you to take a pregnancy test. In the second session you will take the study tablet and complete some psychological tasks on the computer.

Healthy Volunteers Needed For Study Of Reward and Emotion.

Looking for: People who are healthy with no history of psychological disorder.
Expenses: Time and travel expenses will be reimbursed.

We are looking for healthy volunteers aged between 18 and 40 years of age for a study investigating the effects of a single dose of a drug called selegiline on reward and emotional processing. Time and travel expenses will be reimbursed.

Facial Expression Analysis in Mood Assessment

Looking for: Healthy volunteers, aged 18+, to take part in a short video task.
Expenses: Participants will be reimbursed for their time including reasonable travel expenses

The purpose of the study is to learn whether subtle information revealed by people’s facial emotions can tell us more about mood than questionnaires alone. We will perform computerised analysis of video and audio data recorded during the task, which is completed online and lasts approximately 30 minutes. Expenses:

Volunteers Needed For Parkinsons Disease Study.

Looking for: Individuals aged 50-75 who have been diagnosed with Parkinson’s Disease in the last 6 years, to take part in a research study assessing the effects of their usual medication on learning and memory.
Expenses: Time and travel expenses will be reimbursed.

If you express interest, you will be invited to come to the Department of Psychiatry at the Warneford Hospital for 3 study sessions. The first would be an initial screening visit to assess your eligibility to take part. If eligible, you would be invited for a further 2 sessions. One would be shortly after you have taken your usual medication, and the other would be conducted when you are in an ‘off-medication state. This would involve missing/delaying your usual medication for a few hours. Each session would take 2-3 hours of your time and will involve completing a set of computer-based tasks. These sessions would be scheduled approx. 2-3 weeks apart.

Healthy Adults and Stroke Survivors Needed for Motor Learning Study

Looking for: We are looking for volunteers to participate in a study investigating how people learn motor tasks. We are recruiting participants who are neurologically healthy, and those who have had a stroke. This study involves 3 testing sessions each lasting 2 hours, to include an MRI scan, brain stimulation session and motor learning session. MRI is a type of brain scan that allows us to see how the brain is organised, processes information and performs skills like speech or memory. This scan is safe and does not involve any needles or injections.
Expenses: You will be compensated for your time.

Sleep in Borderline Personality Disorder

Looking for: Female participants between the ages of 18 and 35 years with a diagnosis of Borderline Personality Disorder. Our study, called Sleep in Borderline Personality Disorder (SBPD), investigates the effects of a sleep programme on sleep-wake patterns and mood.
Expenses: Participants will be reimbursed for their time and travel expenses

You would be invited to the Department of Psychiatry (Warneford Hospital) for two study visits. During these visits you will complete some questionnaires and computerized tasks and you will be given a selection of wearable and mobile technologies (Fitbit-like devices and phone apps) which measure your sleep and activity throughout your day-to-day life for a period of 8 weeks.

OxPALM: Oxford study on Probiotics and Low Mood

Looking for: Volunteers aged 18 - 55 years who are experiencing low mood and/or loss of interest/motivation to take part in a study investigating the effects of 4-week ingestion of a probiotic or placebo on the processing of emotions (Ethics Reference: R58085/RE001).
Expenses: Time and expenses will be reimbursed.

Are you experiencing low mood?

Looking for: People who are experiencing persistent low mood and not taking antidepressants, to take part in a study investigating how a new medication affects emotional decision making
Expenses: Participants will be reimbursed for their time

We are looking for people who are currently on antidepressants

Looking for: For people who are currently on antidepressants but are still experiencing persistent low mood despite this, to take part in a study investigating how a new medication affects emotional decision making.
Expenses: Participants will be reimbursed for their time

The effect of pramipexole on brain function in healthy volunteers

Looking for: Volunteers needed for a study investigating the effects of a potential novel antidepressant drug on the way the brain processes certain kinds of information
Expenses: You will be compensated for your time.

Volunteers needed for Dementia Prevention Study: European Prevention of Alzheimer’s Dementia (EPAD)

Looking for: People aged 50 or over who have no dementia diagnosis (you may have a diagnosis of mild cognitive impairment or no diagnosis at all). You must be willing to consider taking part in drug trials in future, willing to travel to the Warneford Hospital for annual study assessments involving cognitive tasks, MRI scans and research samples and have a study partner (a relative or friend who could accompany you to study visits)
Expenses: You will be compensated for your travel to the Warneford Hospital.

The European Prevention of Alzheimer’s Dementia (EPAD study) aims to address the urgent need for new treatments designed to prevent Alzheimer’s Dementia. The main study objectives are to: 1. Learn and understand better the factors involved in developing Alzheimer’s dementia. 2. To develop new treatments more quickly which are hoped to prevent Alzheimer’s dementia.

Friends of Oxford Dementia and Ageing Research (OxDARE)

Looking for: Anyone who is interested in finding out about dementia and ageing research volunteer opportunities in the Oxford area.
Expenses: Compensation will vary by study – this will be detailed in the study specific invitations emailed out to registered Friends of OxDARE.

Anyone who is interested in finding out more about dementia and ageing research in Oxford is invited to become a Friend of OxDARE. Friends can choose to register an interest in taking part in future studies and/or receive quarterly newsletters. When new studies get underway, OxDARE researchers will invite interested Friends to take part by email. If you are contacted by one of our researchers, it is your choice whether you would like to participate in their study or not.