We are looking for healthy volunteers aged 18-40 years and fluent in English to take part in a study investigating how a single dose of the medication losartan affects learning and information processing, using a simple computer task. Losartan is currently used to treat high blood pressure. However, we think that it may also enhance the effectiveness of psychological therapies such as Cognitive-Behaviour Therapy. The study involves three appointments of about 5 hours in total.
Lithium can stabilise the highs and lows of mood but requires careful monitoring. We are interested in a new lithium-like medicine called ebselen which might help improve recovery from acute hypo/manic episodes. The study involves adding ebselen to your usual medication during an acute episode of hypo/mania.
Who are we looking for? Healthy fluent English-speaking people aged 18-85 who are not pregnant. You will be asked questions about your medical history to check your suitability for an MRI scan. MRI is a method to measure brain activity that allows us to see how the brain is organised, processes information and performs skills like speech or memory. This scan is safe and does not involve any needles or injections.
Anyone who is interested in finding out more about dementia and ageing research in Oxford is invited to become a Friend of OxDARE. Friends can choose to register an interest in taking part in future studies and/or receive quarterly newsletters. When new studies get underway, OxDARE researchers will invite interested Friends to take part by email. If you are contacted by one of our researchers, it is your choice whether you would like to participate in their study or not.
The European Prevention of Alzheimer’s Dementia (EPAD study) aims to address the urgent need for new treatments designed to prevent Alzheimer’s Dementia. The main study objectives are to: 1. Learn and understand better the factors involved in developing Alzheimer’s dementia. 2. To develop new treatments more quickly which are hoped to prevent Alzheimer’s dementia.
Volunteers should be right handed, have no history of a psychological disorder such as depression, anxiety, or an eating disorder, no previous participation in a study using computerised tasks with emotional faces, and no participation in a drug study within the last 3 months. Central University Research Ethics Committee number: R57219/RE001
Most people with anxiety struggle with worry and stress. Getting help in person can be challenging for a number of reasons, which is why this study aims to find out whether digital Cognitive Behavioural Therapy (a psychological treatment delivered via a mobile app) can help improve anxiety. The study is suitable for adults aged 18 years and above who have persistent problems with anxiety.
We are looking for female participants between the ages of 18 and 35 years to take part in our study called Sleep in Borderline Personality Disorder (SBPD).We require two types of participants: (1) healthy volunteers with no history of a psychological disorder and (2) participants that have been diagnosed with borderline personality disorder. We are investigating the differences in sleep, heart rate, and mood patterns, between people with borderline personality disorder compared with healthy volunteers.
Researchers at the Department of Experimental Psychology, University of Oxford are seeking volunteers for a Transcranial Magnetic Stimulation (TMS) study.
The purpose of this study is to examine how the brain is organised, and how it processes information and performs skills such as thinking and speaking. TMS is a technique that allows us to stimulate the brain by rapid switching of a magnetic field in a coil placed over the head. Participants may experience some discomfort during TMS. By using this technique, we hope to find out how different brain regions contribute to perceptual decision making.
If you express interest, you will be invited to come to the Department of Psychiatry at the Warneford Hospital for 3 study sessions. The first would be an initial screening visit to assess your eligibility to take part. If eligible, you would be invited for a further 2 sessions. One would be shortly after you have taken your usual medication, and the other would be conducted when you are in an ‘off-medication state. This would involve missing/delaying your usual medication for a few hours. Each session would take 2-3 hours of your time and will involve completing a set of computer-based tasks. These sessions would be scheduled approx. 2-3 weeks apart.