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Friends of Oxford Dementia and Ageing Research (OxDARE)

Anyone who is interested in finding out more about dementia and ageing research in Oxford is invited to become a Friend of OxDARE. Friends can choose to register an interest in taking part in future studies and/or receive quarterly newsletters. When new studies get underway, OxDARE researchers will invite interested Friends to take part by email. If you are contacted by one of our researchers, it is your choice whether you would like to participate in their study or not.

Volunteers needed for Dementia Prevention Study: European Prevention of Alzheimer’s Dementia (EPAD)

The European Prevention of Alzheimer’s Dementia (EPAD study) aims to address the urgent need for new treatments designed to prevent Alzheimer’s Dementia. The main study objectives are to: 1. Learn and understand better the factors involved in developing Alzheimer’s dementia. 2. To develop new treatments more quickly which are hoped to prevent Alzheimer’s dementia.

Are you interested in how sleep functions and how sleep affects your mood?

We are looking for female participants between the ages of 18 and 35 years to take part in our study called Sleep in Borderline Personality Disorder (SBPD).We require two types of participants: (1) healthy volunteers with no history of a psychological disorder and (2) participants that have been diagnosed with borderline personality disorder. We are investigating the differences in sleep, heart rate, and mood patterns, between people with borderline personality disorder compared with healthy volunteers.

VOLUNTEERS NEEDED FOR PARKINSON’S DISEASE STUDY

If you express interest, you will be invited to come to the Department of Psychiatry at the Warneford Hospital for 3 study sessions. The first would be an initial screening visit to assess your eligibility to take part. If eligible, you would be invited for a further 2 sessions. One would be shortly after you have taken your usual medication, and the other would be conducted when you are in an ‘off-medication state. This would involve missing/delaying your usual medication for a few hours. Each session would take 2-3 hours of your time and will involve completing a set of computer-based tasks. These sessions would be scheduled approx. 2-3 weeks apart.

Sleep habits and personality traits in Borderline Personality Disorder

We are conducting a study to examine the relationships between sleep quality and timing and personality traits that are associated with Borderline Personality Disorder (BPD).

Volunteers needed for a study investigating the way the brain processes positive and negative information.

The study involves taking a single dose of a commonly used drug (reboxetine or rivastigmine) and completing simple tasks on a computer. You would be invited to the Department of Psychiatry (Warneford Hospital) for 2 study sessions (lasting 1.5 and 4 hours). During the second visit you will take one dose of reboxetine or rivastigmine or a placebo (dummy) tablet. After this we will ask you to complete some simple computer based tasks.

HEALTHY VOLUNTEERS NEEDED FOR STUDY OF REWARD AND EMOTION

We are looking for healthy volunteers aged between 18 and 40 years of age for a study investigating the effects of a single dose of a drug called selegiline on reward and emotional processing. Time and travel expenses will be reimbursed.

Healthy volunteers needed for a drug study investigating how a commonly-used antidepressant influences how people process emotional information about themselves and others.

We will ask you to attend two sessions for approximately 7 hours in total. In the first session we will ask you some questions about your current health and medical history to check your suitability for the study. If you are female, we will also ask you to take a pregnancy test. In the second session you will take the study tablet and complete some psychological tasks on the computer.

Are you experiencing depression despite taking antidepressants?

Duration: Three appointments (one screening visit, two research visits) about 8 hours in total Who can participate? People who feel depressed despite antidepressant treatment, aged 18 to 65 What does the study involve? Psychological tasks, one brain scan using functional Magnetic Resonance Imaging (fMRI), and taking medication for 7 days.

Effects of non-invasive brain stimulation on mood and decision making in healthy adults

The purpose of this study is to examine how the brain processes information and enables us to make decisions. The results will guide our future research aimed at helping individuals who suffer from depression. tDCS is a form of neurostimulation that uses constant, low current delivered to the brain via sensors on the scalp. By using this technique, we hope to find out how different brain regions contribute to making decisions. This study involves 2 visits to the Oxford Centre for Human Brain Activity at the Department of Psychiatry at the University of Oxford. Each session will take no more than 2 hours. Please contact us for further information.

Piloting a learning and decision-making task in healthy adults

The study involves completing simple emotional processing, learning and decision-making tasks once a day every day for up to 4 days. The first 3 days will involve training, and the remaining days will involve a preference test based on what you learned. In total there will be up to 4 sessions. All sessions will take place at an online platform accessible from a computer or a tablet via internet connection.

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