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Neural mechanisms underlying decision making

Who are we looking for? Healthy fluent English-speaking people aged 18-85 who are not pregnant. You will be asked questions about your medical history to check your suitability for an MRI scan. MRI is a method to measure brain activity that allows us to see how the brain is organised, processes information and performs skills like speech or memory. This scan is safe and does not involve any needles or injections.

Friends of Oxford Dementia and Ageing Research (OxDARE)

Anyone who is interested in finding out more about dementia and ageing research in Oxford is invited to become a Friend of OxDARE. Friends can choose to register an interest in taking part in future studies and/or receive quarterly newsletters. When new studies get underway, OxDARE researchers will invite interested Friends to take part by email. If you are contacted by one of our researchers, it is your choice whether you would like to participate in their study or not.

Volunteers needed for Dementia Prevention Study: European Prevention of Alzheimer’s Dementia (EPAD)

The European Prevention of Alzheimer’s Dementia (EPAD study) aims to address the urgent need for new treatments designed to prevent Alzheimer’s Dementia. The main study objectives are to: 1. Learn and understand better the factors involved in developing Alzheimer’s dementia. 2. To develop new treatments more quickly which are hoped to prevent Alzheimer’s dementia.

Daylight Study: Pilot Study of Digital Cognitive Behavioural Therapy for Anxiety

Most people with anxiety struggle with worry and stress. Getting help in person can be challenging for a number of reasons, which is why this study aims to find out whether digital Cognitive Behavioural Therapy (a psychological treatment delivered via a mobile app) can help improve anxiety. The study is suitable for adults aged 18 years and above who have persistent problems with anxiety.

Are you interested in how sleep functions and how sleep affects your mood?

We are looking for female participants between the ages of 18 and 35 years to take part in our study called Sleep in Borderline Personality Disorder (SBPD).We require two types of participants: (1) healthy volunteers with no history of a psychological disorder and (2) participants that have been diagnosed with borderline personality disorder. We are investigating the differences in sleep, heart rate, and mood patterns, between people with borderline personality disorder compared with healthy volunteers.

Researchers at the Department of Experimental Psychology, University of Oxford are seeking volunteers for a Transcranial Magnetic Stimulation (TMS) study.

The purpose of this study is to examine how the brain is organised, and how it processes information and performs skills such as thinking and speaking. TMS is a technique that allows us to stimulate the brain by rapid switching of a magnetic field in a coil placed over the head. Participants may experience some discomfort during TMS. By using this technique, we hope to find out how different brain regions contribute to perceptual decision making.

VOLUNTEERS NEEDED FOR PARKINSON’S DISEASE STUDY

If you express interest, you will be invited to come to the Department of Psychiatry at the Warneford Hospital for 3 study sessions. The first would be an initial screening visit to assess your eligibility to take part. If eligible, you would be invited for a further 2 sessions. One would be shortly after you have taken your usual medication, and the other would be conducted when you are in an ‘off-medication state. This would involve missing/delaying your usual medication for a few hours. Each session would take 2-3 hours of your time and will involve completing a set of computer-based tasks. These sessions would be scheduled approx. 2-3 weeks apart.

Volunteers needed for MRI study of the brain

We need volunteers who are: • Aged 18-35 • Right-handed • In good health and not pregnant • Without metal in their head or body (except fillings) • Without metallic implants (e.g. pacemaker) • and have not had surgery in the past 3 months You will be asked questions about your medical history to check your suitability for an MRI scan. The study involves two visits to the John Radcliffe hospital that would each take about 2 hours of your time. You would be asked to lie still in a scanner and either rest or perform a joystick-based computer task.

Joystick Game MRI study

You will play a computer game in the MRI scanner using a joystick or you will rest, while we scan your brain. The MRI scan takes 1 - 1.5 hours. You will participate on two days, about a week apart. Study takes place at the John Radcliffe Hospital.

Sleep habits and personality traits in Borderline Personality Disorder

We are conducting a study to examine the relationships between sleep quality and timing and personality traits that are associated with Borderline Personality Disorder (BPD).

Volunteers needed for a study investigating the way the brain processes positive and negative information.

The study involves taking a single dose of a commonly used drug (reboxetine or rivastigmine) and completing simple tasks on a computer. You would be invited to the Department of Psychiatry (Warneford Hospital) for 2 study sessions (lasting 1.5 and 4 hours). During the second visit you will take one dose of reboxetine or rivastigmine or a placebo (dummy) tablet. After this we will ask you to complete some simple computer based tasks.

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