The COHORTS collaboration (Consortium On Health Outcomes Research in Transitioning Societies) comprises five of the largest and longest running birth cohort studies in LMICs; Brazil, Guatemala, the Philippines, India and South Africa.
Digital delivery of Behavioural Activation to overcome depression and facilitate social and economic transitions of adolescents in LMICs (DoBAt)
Depression is the leading cause of disability worldwide, and it is particularly problematic among adolescents given the risk for greater depression chronicity across the lifespan. Untreated depression exerts a huge economic toll as it impairs cognitive functioning, interpersonal relationships, interferes with schooling and disrupts work and productivity.
Perinatal depression is very common amongst HIV-positive women, with up to 40% of HIV-positive mothers in parts of southern Africa being affected. Insika Yomama is a treatment trial to evaluate an intervention for depressed HIV-positive women in the perinatal period to enhance child development and reduce maternal depression.
The effect of persistent postnatal depression on children is a major public health issue; the economic costs associated with perinatal mental disorders on child development are substantial with an estimated £8·1 billion per year in the UK alone. The OPT study tested whether a specific parenting intervention improves child outcomes when compared with an intervention not focused on parenting, in a setting where both groups also receive treatment for persistent postnatal depression.
The arrival of a new baby can be an exciting yet vulnerable time for parents; particularly so when a baby has a craniofacial anomaly. Supporting Parents Of Children with Cleft Lip (SPOCCL) is a research study looking at how best to provide extra support to families who have a baby with a cleft lip in the first few weeks of their baby's life.