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New study of more than 1 million people shows statins are safe for people with common neuropsychiatric outcomes, such as new episodes of suicidal behaviours, depression, anxiety or seizures.
Pimavanserin and emotional processing (PANDER) Study
We are investigating how a single dose of pimavanserin (a medication for Parkinson’s-related psychosis) affects emotional processing. The study will involve a 1-hour call to assess eligibility and a single in-person visit at Warneford Hospital (OX3 7JX) involving: physical checks (ECG, blood pressure, BMI), saliva samples and questionnaires, drug administration, a 4-hour break and computerised tasks.
Exploring digital technologies to capture mood, cognition, brain activity and wake/sleep patterns.
The study is investigating regular, at-home use of digital technologies to measure brain activity, cognitive performance, mood, activity and sleep. The study involves 2 in-person sessions, each approximately 2 hours, at the Warneford Hospital, Oxford, OX3 7JX. You will be provided with devices to use during your daily life over a 7-week period.
The effects of citalopram on the brain's response to faces
If you are healthy, without a history of a mental health disorder (like depression), fluent English-speaking, not pregnant, and aged 18 to 40 years, we invite you to take part in a study to investigate the effects of a single dose of citalopram (a medication for depression) on the brain's response to faces using the 7T MRI scanner.
Effort and Antidepressant Study Test (EAST)
The study will take place at Warneford Hospital, and it requires a screening phone call plus 2 in-person visits and will involve a brain scan and a series of computer-based tasks.
Computational Mechanisms underlying human facial emotion recognition
Understanding facial expressions is something all living beings do. It helps us figure out how others feel and how to best respond to social cues around us. We know that many chemicals regulate emotion recognition in our brains, but we do not know exactly how. In this study, our goal is to use eye movement data to build a model that helps us understand how evidence accumulates in the brain when recognising emotions. This will help us get a clearer picture of how different brain chemicals collectively play a role in this process.
The ROSES Study on Sexual Pain
Participants will be asked to fill in an online survey which will ask about how they relate to themselves, particularly their bodies and physical appearance, and about their sexual functioning. This may help us develop better treatment options for individuals with sexual pain. This study is funded by the Health Education England Oxford Clinical Psychology training course. You may ask any questions before deciding to take part by contacting the lead researcher at natascha.niekamp@hmc.ox.ac.uk. This is the link to the study: https://forms.office.com/e/Wr81SXmLdL
GLADE (Glutamate Activity in Depression study)
Study involves a screening visit online or in-person at Warneford Hospital. If deemed eligible, a research visit at the Oxford Centre for Functional MRI of the Brain (FMRIB) at the John Radcliffe Hospital will be offered, which will last around 1.5 - 2 hours. This involves being scanned by an MRS machine whilst viewing a visual stimulus.
GLAD (Genetic Links to Anxiety and Depression)
The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Participants in GLAD are asked to complete a questionnaire, provide a saliva sample and give permission for the study to access to relevant NHS health records.
AADAPT Online - Addressing Young Mums’ & Dads’ Low Mood or Stress And their ParenTing
The AADAPT study aims to see whether a new way to support parents aged 16-24 years who are experiencing low mood and stress is helpful. We would like to see whether an online package of information and activities, supported by volunteer parents who were previously young parents themselves (Parent Buddies) is more helpful than a control group. Could you help us by taking part?
PEACE Study: healthy volunteers
We are looking for healthy volunteers to help understand how the brain works.
Brain Health Centre: healthy volunteers study
Researchers at the University of Oxford are looking for volunteers, aged 16 years or over, to have an MRI brain scan, to help develop ways to measure brain health. For info, email: sameera.shabir@psych.ox.ac.uk
Emotional Processing and Biomarkers Study
We are looking for healthy volunteers aged 16-35 years to take part in a study investigating how levels of certain proteins, so-called growth factors, influence how we process emotional information. The study involves one session of about 3 1/2 hours at the Department of Psychiatry in Headington, Oxford, including a battery of questionnaires and computer games and a small blood sample. The findings might ultimately help develop a simple blood test indicating the risk of developing anxiety in the future.
Losartan and Emotional Learning
We are looking for volunteers aged 18-50 years and fluent in English to take part in a study investigating how a single dose of the medication Losartan affects certain aspects of learning and memory, which we know are important for psychological treatment to work. Losartan is currently used to treat high blood pressure. However, we think that it may also enhance the effectiveness of psychological treatments such as Cognitive-Behavioural Therapy. The study involves one online screening and one face-to-face testing session of about 2-3 hours in total.
Parent mentors required to support young parents with low mood
Are you interested in supporting young parents? The AADAPT study aims to see whether a new way to support parents aged 16-24 years who are experiencing low mood and stress is helpful. We would like to see whether an online package of information and activities, supported by volunteer parents who were previously young parents themselves (Parent Buddies) is more helpful than a control group. Could you be a Parent Buddy and help young parents with the support package?
Transcranial Magnetic Stimulation (TMS) study
The overall motivation for this study is to improve treatment for people suffering from depression. The purpose of this study is to test if novel brain stimulation changes emotion recognition. The study involves Transcranial Magnetic Stimulation (TMS), in which we place a stimulation coil over the head, which generates a magnetic field that passes painlessly through the skull to stimulate the brain. The effect lasts for a few minutes. Participants do not normally notice any effect of stimulation, though some may experience short-lasting discomfort during TMS, which can usually be alleviated by adjusting the coil position. By conducting this research, we hope to better understand the effect of brain stimulation on emotional processing, which will inform efforts to improve the treatment of depression.
Communicating health-related information: the CICERO online randomised controlled trial
How the benefits and harms of medical interventions are communicated affects how well patients understand it and can impact their decision-making and confidence. The CICERO study will compare three different ways of communicating available information on medical interventions. The study consists of a single session lasting about 20 minutes.
Healthy Volunteers Needed For Study Of Reward and Emotion.
We are looking for healthy volunteers aged between 18 and 40 years of age for a study investigating the effects of a single dose of a drug called selegiline on reward and emotional processing. Time and travel expenses will be reimbursed.
Volunteers Needed For Parkinsons Disease Study.
If you express interest, you will be invited to come to the Department of Psychiatry at the Warneford Hospital for 3 study sessions. The first would be an initial screening visit to assess your eligibility to take part. If eligible, you would be invited for a further 2 sessions. One would be shortly after you have taken your usual medication, and the other would be conducted when you are in an ‘off-medication state. This would involve missing/delaying your usual medication for a few hours. Each session would take 2-3 hours of your time and will involve completing a set of computer-based tasks. These sessions would be scheduled approx. 2-3 weeks apart.