Department of Psychiatry

NIHR Oxford Health Biomedical Research Centre (BRC)

Oxford Health Biomedical Research Centre aims to create a platform to deliver high quality experimental medicine research on new treatments and procedures to improve lives.

Heart and Brain Ageing Group

Nearly a third of dementia cases can be prevented by modifying our lifestyle, in particular our cardiovascular health. While we know that “what’s good for the heart is good for the brain”, we still don’t entirely know why. Our group investigates this heart-brain link in detail, by studying how the health of our heart and large blood vessels affect the brain and memory as we grow older.

Translational NeuroStimulation Laboratory

We aim to understand processes of selective attention and action, learning and memory in the human brain. Through experiments in healthy volunteers and patients with brain disorders we seek to characterize how information processing networks respond (adaptively or maladaptively) when challenged by interference. Our motivation is to develop rational neurocognitive intervention strategies to help promote recovery from conditions such as depression and brain injury.

Computational Psychiatry

Using computer models of behaviour, we aim to better understand anxiety and depression, and to guide the development of novel treatments.

Translational Neuroimaging

Neuroimaging provides a window into the living brain, and is an increasingly vital experimental medicine tool for neuro-psychiatric disease. With a particular focus on early and pre-clinical disease, we explore how the brain changes before symptoms take hold.

Psychopharmacology and Emotion Research Laboratory (PERL)

We explore how the brain processes emotional information and how this is influenced by brain chemicals and medicines. This helps us to understand disorders such as depression and anxiety and to understand and contribute to the development of drug and psychological treatments.

Clinical Psychopharmacology

Our research aims to understand how psychotropic drugs work at molecular level. By exploring this through clinical research in patients we contribute to the development of new evidence-based pharmacological treatments for severe mental illness.

Neurobiology of Ageing

Why do some people suffer from depression and memory loss as they age, whereas others stay well for the whole of their lives? We examine the effect of genes and life history on ageing using neuropsychology and neuro-imaging techniques as part of large scale epidemiological and experimental medicine studies.

Oxford Brain-Body Research into Eating Disorders

We work to understand the cognitive, biological, emotional and somatic processes underpinning the severe eating disorder Anorexia Nervosa in particular, and Eating Disorders in general. Our trans-disciplinary research, involving clinicians and neuroscientists, aims to translate research findings into novel treatment strategies.

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