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A team of Oxford researchers has won a grant from the University’s Covid-19 Research Response Fund to study the effects of online cultural experiences on mental health. This new study will use the unique opportunity of lockdown and social distancing to gather new evidence.
Bipolar Depression Mental illness Mood Randomised trial Research-based
A daily and weekly remote symptom monitoring system for patients with over a decade of use in research and clinical service
Alzheimer's Brain function Brain imaging Cognitive Dementia Magnetic Resonance Imaging (MRI) Medical co-morbidity Medicine
Nearly a third of dementia cases can be prevented by modifying our lifestyle, in particular our cardiovascular health. While we know that “what’s good for the heart is good for the brain”, we still don’t entirely know why. Our group investigates this heart-brain link in detail, by studying how the health of our heart and large blood vessels affect the brain and memory as we grow older.
We want to understand how best to design a mental health databank which identifies active ingredients in preventing and treating depression and anxiety in young people. We have brought on board young people's voices on how to measure such active ingredients, and how such a databank might be designed, used, and shared. Along with colleagues in Cambridge, we work closely with young people, professionals, and researchers in South Africa and India. We welcome other collaborations and enquiries.
In partnership with Kindred2, SEEN is a research project to develop and pilot curriculum for Key Stage 3 pupils. It aims to embed the key principles of early child development and neuroscience for young people.
We aim to understand processes of selective attention and action, learning and memory in the human brain. Through experiments in healthy volunteers and patients with brain disorders we seek to characterize how information processing networks respond (adaptively or maladaptively) when challenged by interference. Our motivation is to develop rational neurocognitive intervention strategies to help promote recovery from conditions such as depression and brain injury.
Clinical trial Mental illness Psychosis Schizophrenia Treatment Treatment trials
We undertake research across the translational spectrum, ranging from basis science studies, through to trials of new treatments and approaches for psychosis, right through to researching clinical services and their effectiveness. We work closely with the Oxfordshire Early Intervention in Psychosis Service in Oxford Health NHS FT. This service provides high quality, multi-discliplinary care for people experiencing first episode of psychosis and their families. We also lead the Early Intervention Psychosis network for the NHS in the South of England, providing the opportunity to speed up the translation of new research findings into routine clinical care. You can find out more about our current studies below.
This research group is interested in understanding how best to support the mental health of children attending school. We are keen to learn about what young people need, which factors influence their wellbeing, and how they would like to access help if they have mental health difficulties. We have been running the OxWell School Survey since April 2019, with pupils completing an online survey. We work closely with schools, local authorities and mental health commissioners and services. We welcome collaborations.
Clinical trial Depression Evidence Based Medicine Mental illness
We are an international multidisciplinary group of researchers, clinicians (both psychiatrists and psychologists), statisticians, methodologists and students who aim to improve the current treatment practice in the NHS and across the world, using innovative approaches from artificial intelligence and machine learning, to digital mental health and bioethics.
We aim to better understand the determinants of student wellbeing and academic success, and to evaluate the mental health support needs of students at Oxford.
Developing new analysis tools for understanding human brain activity
Alzheimer's Child development Community Mental Health Services Neuroscience Parenting Prevention Psychosis Schizophrenia
We conduct independent ethics research and we deliver ethical guidance for a range of scientific and clinical studies in the Oxford Department of Psychiatry and Neuroscience. We also work with a variety of international institutions and researchers. Our core research interests involve young people, mental health and neuroscience innovations in a global context.
Anxiety Behavioural models Brain function Brain imaging Decision-making Depression Neuroscience
Using computer models of behaviour, we aim to better understand anxiety and depression, and to guide the development of novel treatments.
Behaviour Brain Brain imaging Cognitive Cognitive models Decision-making Dopamine Functional imaging Genetics Magnetic Resonance Imaging (MRI) Magnetoencephalography (MEG) Mood Neuroimaging Neuroscience Pharmacology Risk factors Schizophrenia Stress
Our research aims to understand how individual genes contribute to the complex brain functions that are impaired in people with psychiatric disorders. By understanding these links we hope to improve treatments for these disorders.
Alzheimer's Case registers Clinical trial Dementia Dopamine Neuroscience Parkinson's
The Translational Neuroscience and Dementia Research Group undertake translational research ranging from mechanisms to drug development, and from discovery to qualification of molecular and imaging biomarkers in both Alzheimer’s disease and Parkinson’s disease and in related dementia disorders. The group, led by Professor Noel Buckley, comprises molecular and cellular biology scientists, computational biologists and informaticians working with molecular, clinical and imaging datasets. We have three main areas of activity, all aiming towards secondary prevention of dementia. By understanding disease mechanisms we seek potential therapeutics; through discovery of biomarkers we hope to enable preventative trials, and with informatics we utilise large biological and clinical datasets in the support of translational neuroscience.
Alzheimer's Brain Brain function Brain imaging Clinical trial Cognitive models Cohorts Dementia Empirical Functional imaging Genetics Magnetic Resonance Imaging (MRI) Medical imaging Neuroimaging Neurology Neuroscience Parkinson's Risk factors Whitehall Study
Neuroimaging provides a window into the living brain, and is an increasingly vital experimental medicine tool for neuro-psychiatric disease. With a particular focus on early and pre-clinical disease, we explore how the brain changes before symptoms take hold.
The Oxford Autism Research Centre brings together scientists, charities and service providers from across Oxfordshire and the surrounding regions.
Depression Economic recession Epidemiology Mental illness Prevention Risk factors Suicide
Our mission is to promote the healthy mental and physical development of children and their families around the globe, irrespective of their life circumstances. Our work focusses on development in the face of adversity, including perinatal mental health difficulties, life threatening conditions such as HIV and cancer, and situations of violence, war and poverty.
Our research includes projects in the epidemiology of mental illness and violent crime, violence risk assessment, prison health, pharmacoepidemiology studies, forensic services, and suicide and self-harm in prisoners and offenders.