Contact information
George Chapman
BSc(Hons) MB ChB MRCPsych
Clinical Researcher
Biography
I joined the Department of Psychiatry, University of Oxford in September 2025. Here I am working with Dr Rob McCutcheon on clinical studies into the causes of, and possible new treatments for, schizophrenia and other psychoses.
Before moving to Oxford, I was a core psychiatry trainee in North London and NIHR Academic Clinical Fellow at University College London, where I worked with Professor Rob Howard, studying the fixity of delusions.
Prior to this, I was a clinical research fellow within Professor Oliver Howes's psychiatric imaging group, based at King's College London and Imperial College London. Here I worked on PET and fMRI studies in people with psychosis and healthy volunteers.
Interests
I am broadly interested in the psychopharmacology and cognitive neuroscience of psychiatric disorders, with a particular focus on delusions and psychosis. I am looking to start a PhD/MD in this area shortly. Please reach out to me if you have similar interests and would like to chat!
Recent publications
Cortical 5-HT2A receptors in depression and suicide: a systematic review and meta-analysis of in vivo and post-mortem imaging studies.
Journal article
Chapman GE. et al, (2025), Mol Psychiatry, 30, 6045 - 6062
Effects of antipsychotics on human cognitive function: causal evidence from healthy volunteers following sustained D2/D3 antagonism, D2/D3 partial agonism and placebo.
Journal article
Osugo M. et al, (2025), Mol Psychiatry, 30, 5315 - 5325
ntipsychotics cause reversible structural brain changes within one week.
Journal article
Selvaggi P. et al, (2025), Neuropsychopharmacology, 50, 1275 - 1283
Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour.
Journal article
Osugo M. et al, (2025), Nat Commun, 16
Understanding variability: the role of meta-analysis of variance.
Journal article
Howes OD. and Chapman GE., (2024), Psychol Med, 54, 1 - 4
ipiprazole-Associated QT Prolongation in a Healthy Study Volunteer: A Case Report and Literature Review.
Journal article
Chapman GE. et al, (2024), J Clin Psychopharmacol, 44, 591 - 594
The Effects of Developmental Stress on Dopaminergic Function in Adulthood: A Systematic Review and Meta-Analysis
Journal article
Noar A. et al, (2024), BJPSYCH OPEN, 10, S68 - S68
Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study.
Journal article
Geriatric Medicine Research Collaborative ., (2023), Eur Geriatr Med, 14, 325 - 332
Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes.
Journal article
Howes OD. et al, (2023), Neuropsychopharmacology, 48, 151 - 167
Google search behaviour relating to perinatal mental wellbeing during the United Kingdom's first COVID-19 lockdown period: a warning for future restrictions.
Journal article
Chapman GE. et al, (2021), Arch Womens Ment Health, 24, 681 - 686
Psych Socs: student-led psychiatry societies, an untapped resource for recruitment and reducing stigma.
Journal article
Pandian H. et al, (2020), BJPsych Bull, 44, 91 - 95
Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day.
Journal article
Geriatric Medicine Research Collaborative ., (2019), BMC Med, 17
Studies on long term behavioural changes in group-housed rat models of brain and spinal cord injury using an automated home cage recording system.
Journal article
Yip PK. et al, (2019), J Neurosci Methods, 321, 49 - 63