Katharine Smith
BA (Cantab), BMBCh (Oxon), MRCPsych, DM (Oxon)
Clinical Researcher, Honorary Consultant Psychiatrist
My main area of interest is in the use of evidence-based strategies to answer real world clinical questions in mental health. Recently, I have been leading a multidisciplinary group of researchers and clinicians from the Oxford Precision Psychiatry Lab in developing summaries of guidance for mental health clinicians to help in addressing clinical problems presented by COVID-19. This has involved collaboration with national and international experts in the fields of telepsychiatry, suicide and self-harm, perinatal psychiatry and domestic violence research (https://oxfordhealthbrc.nihr.ac.uk/our-work/oxppl/covid-19-and-mental-health-guidance/).
I also have an interest in research in the psychopharmacology and cognitive impacts of mood disorders. As part of my work on the NIHR Oxford Cognitive Health Clinical Research Facility, I am involved as a researcher in complex cognitive health research working with Principal Investigators, research networks, local R&D, and Oxford Health NHS Foundation Trust. More recently I have been involved as Principal and Chief Investigator in a study of cognitive dysfunction after recovery from clinical depression. I have an Honorary Consultant contract with Oxford Health NHS Foundation Trust and work clinically in the Bipolar Disorder Research Clinic.
Recent publications
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Engagement and attrition in digital mental health: current challenges and potential solutions.
Journal article
Smith KA. et al, (2025), NPJ Digit Med, 8
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Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo-controlled, double-blind, randomised trial in the UK.
Journal article
Browning M. et al, (2025), Lancet Psychiatry
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Personalising Antidepressant Treatment for Unipolar Depression Combining Individual Choices, Risks and big Data: The PETRUSHKA Tool: Personnalisation du traitement antidépresseur de la dépression unipolaire associant choix individuels, risques et mégadonnées: l'outil PETRUSHKA.
Journal article
Ostinelli EG. et al, (2025), Can J Psychiatry
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Triangulating evidence from the GALENOS living systematic review on trace amine-associated receptor 1 (TAAR1) agonists in psychosis.
Journal article
Smith KA. et al, (2024), Br J Psychiatry, 1 - 9
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An online evidence-based dictionary of common adverse events of antidepressants: a new tool to empower patients and clinicians in their shared decision-making process.
Journal article
Hong JSW. et al, (2024), BMC Psychiatry, 24