Contact information
George Chapman
BSc(Hons) MB ChB MRCPsych
Clinical Researcher
Biography
I joined the Department of Psychiatry, University of Oxford in September 2025. Here I am working with Dr Rob McCutcheon on clinical studies into the causes of, and possible new treatments for, schizophrenia and other psychoses.
Before moving to Oxford, I was a core psychiatry trainee in North London and NIHR Academic Clinical Fellow at University College London, where I worked with Professor Rob Howard, studying the fixity of delusions.
Prior to this, I was a clinical research fellow within Professor Oliver Howes's psychiatric imaging group, based at King's College London and Imperial College London. Here I worked on PET and fMRI studies in people with psychosis and healthy volunteers.
Interests
I am broadly interested in the psychopharmacology and cognitive neuroscience of psychiatric disorders, with a particular focus on delusions and psychosis. I am looking to start a PhD/MD in this area shortly. Please reach out to me if you have similar interests and would like to chat!
Recent publications
On the fixed nature of delusions
Journal article
Chapman GE. et al, (2026), Nature Mental Health, 4, 912 - 925
Cortical 5-HT2A receptors in depression and suicide: a systematic review and meta-analysis of in vivo and post-mortem imaging studies.
Journal article
Chapman GE. et al, (2025), Mol Psychiatry, 30, 6045 - 6062
Effects of antipsychotics on human cognitive function: causal evidence from healthy volunteers following sustained D2/D3 antagonism, D2/D3 partial agonism and placebo.
Journal article
Osugo M. et al, (2025), Mol Psychiatry, 30, 5315 - 5325
Antipsychotics cause reversible structural brain changes within one week.
Journal article
Selvaggi P. et al, (2025), Neuropsychopharmacology, 50, 1275 - 1283
Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour.
Journal article
Osugo M. et al, (2025), Nat Commun, 16
Understanding variability: the role of meta-analysis of variance.
Journal article
Howes OD. and Chapman GE., (2024), Psychol Med, 54, 3233 - 3236
Aripiprazole-Associated QT Prolongation in a Healthy Study Volunteer: A Case Report and Literature Review.
Journal article
Chapman GE. et al, (2024), J Clin Psychopharmacol, 44, 591 - 594
The Effects of Developmental Stress on Dopaminergic Function in Adulthood: A Systematic Review and Meta-Analysis
Journal article
Noar A. et al, (2024), BJPSYCH OPEN, 10, S68 - S68
Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study.
Journal article
Geriatric Medicine Research Collaborative ., (2023), Eur Geriatr Med, 14, 325 - 332
Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes.
Journal article
Howes OD. et al, (2023), Neuropsychopharmacology, 48, 151 - 167
Google search behaviour relating to perinatal mental wellbeing during the United Kingdom's first COVID-19 lockdown period: a warning for future restrictions.
Journal article
Chapman GE. et al, (2021), Arch Womens Ment Health, 24, 681 - 686
Psych Socs: student-led psychiatry societies, an untapped resource for recruitment and reducing stigma.
Journal article
Pandian H. et al, (2020), BJPsych Bull, 44, 91 - 95
Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day.
Journal article
Geriatric Medicine Research Collaborative ., (2019), BMC Med, 17
Studies on long term behavioural changes in group-housed rat models of brain and spinal cord injury using an automated home cage recording system.
Journal article
Yip PK. et al, (2019), J Neurosci Methods, 321, 49 - 63