Research groups
Websites
Buddhiprabha Erabadda
PhD
Postdoctoral Researcher
Research and Interests
My primary research interests lie in utilising bioinformatics tools and machine learning for the discovery of biomarkers and disease subtypes in neurodegenerative diseases. Specifically, I focus on Parkinson's disease and Alzheimer's disease. My current work is funded by The Michael J. Fox Foundation (MJFF) and Alzheimer's Research UK (ARUK).
I am part of the Translational Neuroscience & Dementia Research group, working with Dr Laura Winchester, Prof. Alejo J. Nevado-Holgado, and other colleagues on our team at the Department of Psychiatry.
In addition to our extended team in the Department of Psychiatry and Department of Biochemistry, I collaborate with colleagues from the University of Washington, University College London, and the University of Glasgow who share the same research interests as our team.
Background
I have a background in Computer Science, and I completed my PhD at the Centre for Vision, Speech, and Signal Processing, University of Surrey, UK. I joined the Centre for Population Health Sciences, College of Medicine and Veterinary Medicine at the University of Edinburgh as a postdoctoral researcher, soon after my PhD. I worked with the Precision Medicine team there, working towards identifying drug targets for complex genetic diseases using statistical and machine learning based models. Now I work at the Department of Psychiatry, Medical Sciences Division, here at the University of Oxford.
recent publications:
• Ali, M., Erabadda, B., Chen, Y., Xu, Y., Gong, K., Liu, M., ... Winchester, L & Cruchaga, C. (2025). Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases. Nature Medicine, 1-11.
• Iakovliev, A., Castellini-Pérez, O., Erabadda, B., PRECISESADS Clinical Consortium, PRECISESADS Flow Cytometry Consortium, Martín, J., ... & Spiliopoulou, A. (2025). Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis. Genes & Immunity, 1-12.
• McKeigue, P. M., Iakovliev, A., Erabadda, B., Colhoun, H. M., & Spiliopoulou, A. (2025). Genome-Wide Aggregated Trans-Effects Analysis Implicates Deficient Type III Interferon Signaling as a Key Cause of Inflammatory Bowel Disease. Inflammatory Bowel Diseases, izaf214.
• Zhou, X., Iakovliev, A., McGurnaghan, S., Erabadda, B., Hayward, C., McKeigue, P. M., ... & Colhoun, H. M. (2025). Genome-wide aggregated trans effects analysis for circulating proteins indicates a key role of immune checkpoints in type 1 diabetes. Diabetes, db250067.