Research groups
Colleges
Chloe Wigg
BSc (Hons), MRes
DPhil Candidate | Lead of the Mental Wellbeing Working Group in Psychiatry
I am a DPhil Candidate within the Psychopharmacology and Emotion Research Lab (PERL), supervised by Dr Susannah Murphy and Professor Catherine Harmer.
My research focuses on investigating the potential effects of ketamine, a medication, on motivation and anhedonia in individuals who are taking an antidepressant but still experiencing symptoms of depression. Through my DPhil thesis, I strive to advance our knowledge in this important area and make a positive impact on the lives of those with depression. Feel free to contact me via email or twitter for more information about my research.
Recent publications
The cognitive neuroscience of ketamine in major depression.
Journal article
Costi S. et al, (2025), Brain, 148, 3496 - 3504
Direct serotonin release in humans shapes aversive learning and inhibition.
Journal article
Colwell MJ. et al, (2024), Nat Commun, 15
Direct serotonin release in humans shapes decision computations within aversive environments
Preprint
Colwell MJ. et al, (2023)
ssociations Between Statin Use and Negative Affective Bias During COVID-19: An Observational, Longitudinal UK Study Investigating Depression Vulnerability.
Journal article
Gillespie AL. et al, (2022), Biol Psychiatry, 92, 543 - 551
Treatment-resistant depression: Therapeutic options when first-line treatments fail
Journal article
Wigg C. and Costi S., (2022), BJPsych Advances, 28, 4 - 8
