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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To compare individual active drugs (antidepressants and benzodiazepines) and placebo in terms of efficacy and acceptability in the acute treatment of panic disorder, with or without agoraphobia. To rank individual active drugs for panic disorder (antidepressants, benzodiazepines and placebo) according to their effectiveness and acceptability. To explore heterogeneity and inconsistency between direct and indirect evidence in the network meta-analyses.

Original publication




Journal article


Cochrane Database of Systematic Reviews

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