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The relatively new class of antidepressant, the selective serotonin reputake inhibitors (SSRIs), may be better tolerated than the older tricyclic antidepressants. This review compares the efficacy of SSRIs with other antidepressants.

Original publication




Journal article


Cochrane Database Syst Rev

Publication Date



University of Oxford, Department of Psychiatry, Warneford Hospital, Oxford, UK, OX3 7JK.


Antidepressive Agents, Depressive Disorder, Humans, Serotonin Uptake Inhibitors