Contact information
Collaborators
Patricia Anna Handschuh
MD, BA
Academic Visitor
- PhD candidate, Medical University of Vienna
- Consultant Psychiatrist, Medical University of Vienna (currently on academic leave as an Academic Visitor at the University of Oxford)
- Honorary Consultant Psychiatrist
ABOUT ME AND MY RESEARCH
I am a psychiatrist, researcher and PhD candidate in the field of clinical neurosciences, with a particular interest in how environmental factors and lifestyle modify biological processes related to mental health. My research explores how these factors interact with processes like hormonal and epigenetic modifications, which act as intermediaries, potentially affecting brain function and structure in conditions such as depression and Seasonal Affective Disorder.
While I am primarily affiliated with the Department of Psychiatry and Psychotherapy at the Medical University of Vienna (as a senior team member of the Neuroimaging Labs (NIL) – PET & MRI & EEG & TMS & Chemical Lab led by Prof. Rupert Lanzenberger), I am currently in Oxford to expand my research into the promising field of microbiome research and its potential implications for psychiatric conditions, in collaboration with Prof. Phil Burnet and Dr. Amedeo Minichino. My primary expertise lies in neuroimaging (using techniques such as PET, MRI, and MRS), and I aim to integrate these techniques with microbiome research in the future, exploring how the microbiome might influence neurotransmitter metabolism and brain function. My time here is dedicated to deepening my understanding of these intersections and fostering international collaborations that combine in vivo imaging with microbiome analysis, with the aim of developing more effective, personalized treatment approaches for psychiatric conditions.
In addition to my research, I am normally serving as a consultant liaison psychiatrist at the Department of Psychiatry and Psychotherapy at the Medical University of Vienna, while also working as a senior consultant at a forensic-therapeutic centre in Austria, where my work focuses on supporting individuals with mental health conditions, particularly those experiencing schizophrenia.
If you are interested in learning more about my work or discussing potential collaborations, please feel free to reach out!
Key publications
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Summer and SERT: Effect of daily sunshine hours onSLC6A4promoter methylation in seasonal affective disorder
Preprint
Handschuh PA. et al, (2024)
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Effect ofMAOADNA methylation on humanin vivoprotein expression measured by [11C]harmine PET in healthy and depressed individuals
Preprint
Handschuh PA. et al, (2022)
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Effects of gender-affirming hormone therapy on gray matter density, microstructure and monoamine oxidase A levels in transgender subjects
Preprint
Handschuh PA. et al, (2022)
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The influence of sex steroid treatment on insular connectivity in gender dysphoria
Preprint
Reed MB. et al, (2022)
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Gender-affirming hormone treatment - A unique approach to study the effects of sex hormones on brain structure and function.
Journal article
Kranz GS. et al, (2020), Cortex, 129, 68 - 79
Recent publications
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Journal article
Bozic I. et al, (2025), Eur Neuropsychopharmacol, 93, 66 - 67
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Journal article
Handschuh PA. et al, (2025), World Journal of Biological Psychiatry
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Preprint
Handschuh PA. et al, (2024)
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Journal article
Handschuh PA. et al, (2024), Neuroimage, 297
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Journal article
Reed MB. et al, (2024), Eur J Nucl Med Mol Imaging, 51, 2625 - 2637