Clinical and psychometric correlates of dopamine D2 binding in depression.
Shah PJ., Ogilvie AD., Goodwin GM., Ebmeier KP.
Single photon emission tomography (SPET) with the dopamine D2/3 ligand 123I-IBZM gives a semi-quantitative estimate of dopamine binding. In depressed patients, we predicted evidence of reduced function, i.e. increased binding, particularly in more retarded patients.