Department Seminar Series | Pharmacogenetic and Pharmaco-Epidemiological Approaches to Synergistically Boost Precision Pharmacotherapy in Psychiatry

Psychiatry is in need of tools to improve personalized treatment given the high rates of adverse drug reactions and generally low remission rates. Here, I discuss how pharmaco-genetics approaches have elucidated that some treatment outcomes in severe psychiatric disorders are associated with polygenic risk profiles. I also give examples of real-world epidemiological approaches that have potential to curtail risks ofpsychotropic mediation use and improve response rates. Finally, I summarize some of the insights Mendelian Randomization studies conducted at my lab have provided. Overall, the aim of the talk is to critically appraise the hypothesis that more personalized prescribing is possible in psychiatry. I look forward to critical thoughts, suggestions, lively discussions, and possible future collaborations.

Hosted in the Seminar Room, to attend via Zoom, please use the joining details below:

• https://zoom.us/j/98643323773?pwd=bL0TW4vweAlQzIlL5VEFHKYiEaVYPl.1
• Meeting ID: 986 4332 3773
• Passcode: 758174