Simeen Tabassi Morfrad

Dr Simeen Tabassi Mofrad is a Research Fellow in Medical Sciences Division of University of Oxford, and a Research Member of the Common Room at Wolfson College. She is interested in diagnostic biomarkers of neurodegenerative diseases, in particular, by investigating neuroinflammatory and genetic characteristics and their impacts on brain behaviour.

With expertise in interdisciplinary neuroscience, brain mapping, and network analysis, and by harnessing large-scale neuroimaging datasets, she has established normative, sex-specific benchmarks based on volumetric alterations of grey matter in subcortical regions that distinguish healthy ageing from pathological neurodegeneration. These reference trajectories serve multiple purposes in neuroscience and clinical research, including guiding regenerative strategies and informing therapeutic interventions by identifying subcortical regions most vulnerable to age-related atrophy and inflammation.

By bridging interdisciplinary neuroscience with clinical application, her work seeks to deepen understanding of brain ageing and neurodegeneration, with the ultimate aim of delaying cognitive impairment and dementia and informing the development of novel therapeutic strategies.

Sources of Funding  

Netherlands Organization for Scientific Research (NWO) (2024 - 2026)

Leiden University Fund (2019 - 2021)