Shorter communications editor: Niels keiding: Accounting for mutation effects in the additive genetic variance-covariance matrix and its inverse
Wray NR.
Procedures for calculating the additive genetic variance-covariance matrix and its inverse are adapted to accommodate the occurrence of mutations in the genome. The inverse matrix can be used in mixed model methodology for best linear unbiased prediction of breeding values or for variance component estimation under a genetic model that includes mutation effects.