Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Total plasma tryptophan was significantly lower in 12 depressed patients than in 12 normal controls. The ratio of total tryptophan to neutral amino acids was also decreased in the depressed patients suggesting that tryptophan availability to the brain might be reduced. There was no correlation between basal tryptophan concentrations in the depressed subjects and the subsequent neuroendocrine response to intravenous tryptophan.


Journal article


J Affect Disord

Publication Date





27 - 31


Adult, Depressive Disorder, Female, Growth Hormone, Humans, Isoleucine, Leucine, Male, Middle Aged, Prolactin, Tryptophan, Tyrosine, Valine