New drug targets in psychiatry: Neurobiological considerations in the genomics era.
Journal article
Harrison PJ. et al, (2022), Neurosci Biobehav Rev, 139
Kalirin as a Novel Treatment Target for Cognitive Dysfunction in Schizophrenia.
Journal article
Mould AW. et al, (2022), CNS Drugs, 36, 1 - 16
The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice.
Journal article
Goolam M. et al, (2020), Nat Commun, 11
Cellular calcium in bipolar disorder: systematic review and meta-analysis.
Journal article
Harrison PJ. et al, (2019), Mol Psychiatry
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study.
Journal article
Atkinson LZ. et al, (2019), Trials, 20
Publisher Correction: Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy.
Journal article
Nelson AC. et al, (2018), Nat Commun, 9
Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters.
Journal article
Jansz N. et al, (2018), Nat Struct Mol Biol, 25, 766 - 777
Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.
Journal article
Senft AD. et al, (2018), Cell Rep, 24, 1977 - 1985.e7
Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells.
Journal article
Elias S. et al, (2018), Sci Rep, 8
Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation.
Journal article
Nelson AC. et al, (2017), Sci Rep, 7
Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.
Journal article
Tonks ID. et al, (2017), Oncogene, 36, 3789 - 3795
PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.
Journal article
Almeida M. et al, (2017), Science, 356, 1081 - 1084
The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development.
Journal article
Ahmed MI. et al, (2016), Development, 143, 1663 - 1673
Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy.
Journal article
Nelson AC. et al, (2016), Nat Commun, 7
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development.
Journal article
Costello I. et al, (2015), Genes Dev, 29, 2108 - 2122
Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation.
Journal article
Mould AW. et al, (2015), PLoS Genet, 11
Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.
Journal article
Mould AW. et al, (2013), Epigenetics Chromatin, 6
The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice.
Journal article
Morgan MAJ. et al, (2013), PLoS One, 8
DNA methylation signatures in colorectal cancer
Conference paper
Whitehall V. et al, (2012), JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27, 28 - 28
Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta.
Journal article
Mould A. et al, (2012), Genes Dev, 26, 2063 - 2074