Contact information
Research groups
Helen Rowland
PhD
Postdoctoral Researcher
I am a postdoctoral researcher within the Translational Neuroscience and Dementia Research group. My research interests are in using stem-cell derived neural cells including neurons, astrocytes and microglia, to create better models of Alzheimer’s disease to improve our understanding of disease mechanisms and identify and screen new therapeutic targets.
I am currently involved in projects investigating how a vast array of clinical measures from patients with Alzheimer’s disease can be recapitulated using the patient’s own cells, and how artificial intelligence approaches can be used to distinguish the phenotypic signature of stem-cell derived neural cells containing risk genes for Alzheimer’s disease.
Recent publications
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Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers.
Journal article
Rowland HA. et al, (2025), Stem Cells, 43
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Inhibition of insulin-degrading enzyme in human neurons promotes amyloid-β deposition
Journal article
Rowland HA. et al, (2023), Neuronal Signaling
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Deep learning-based cell profiling based on neuronal morphology
Preprint
Liu Q. et al, (2023)
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iPSC-Astrocyte morphology reflects patient clinical markers
Preprint
Rowland HA. et al, (2023)
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Temporal transcriptional control of neural induction in human induced pluripotent stem cells.
Journal article
Gupta S. et al, (2023), Front Mol Neurosci, 16