Jacinta O'Shea
Jacinta O'Shea
DPhil, MSc, MA, BA
Associate Professor & Wellcome/Royal Society Sir Henry Dale Fellow
Manipulating brain plasticity for therapeutic gain
I am a cognitive neuroscientist interested in cognition, action and neurobehavioural plasticity. In our group we use neural interference methods, combined with neuroimaging and detailed cognitive and behavioural probes, to make reverse inference about how information processing is organised in the healthy brain. We aim to leverage these insights within an experimental medicine framework to develop novel therapeutics to aid individuals affected by psychiatric or neurological conditions. For more information see our research group website.
Google scholar link: https://scholar.google.co.uk/citations?hl=en&user=BD8dNTUAAAAJ
Key publications
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Effect of Prefrontal Cortex Stimulation on Regulation of Amygdala Response to Threat in Individuals With Trait Anxiety: A Randomized Clinical Trial.
Ironside M. et al, (2019), JAMA Psychiatry, 76, 71 - 78
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Age-related decline in cortical inhibitory tone strengthens motor memory
Petitet P. et al, (2021), NeuroImage, 118681 - 118681
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Induced sensorimotor cortex plasticity remediates chronic treatment-resistant visual neglect.
O'Shea J. et al, (2017), Elife, 6
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Predicting behavioural response to TDCS in chronic motor stroke.
O'Shea J. et al, (2014), Neuroimage, 85 Pt 3, 924 - 933
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The effect of pulse shape in theta-burst stimulation: Monophasic vs biphasic TMS.
Wendt K. et al, (2023), Brain Stimul, 16, 1178 - 1185
Recent publications
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The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper.
Antal A. et al, (2024), Clin Neurophysiol
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Influence of time of day on resting motor threshold in clinical TMS practice.
Wendt K. et al, (2023), Clin Neurophysiol, 155, 65 - 67
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Bifrontal transcranial direct current stimulation normalises learning rate adjustment in low mood
Sarrazin V. et al, (2023)
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Stimulating human prefrontal cortex increases reward learning.
Overman MJ. et al, (2023), Neuroimage
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The effect of pulse shape in theta-burst stimulation: monophasic vs biphasic TBS
Wendt K. et al, (2023)