I studied medicine at Cambridge and Oxford before training in psychiatry in the Oxford region. My academic training was supported by a Wellcome Trust Research Training Fellowship and a NIHR Clinical Lectureship.
While a Clinical Senior Lecturer at IOPPN, I worked as a consultant psychiatrist for South London and Maudsley NHS Foundation Trust, and served as Associate Clinical Director for the Early Intervention pathway. I now work as a consultant for the Adult Mental Health Team in West Oxfordshire.
My research interests have included using advanced meta-analysis of clinical trial data to clarify treatment mechanisms, and also understanding vulnerability and resilience mechanisms, and potential diagnostic markers, through techniques such as Magnetic Resonance Spectroscopy.
Glyceryl Trinitrate in First Episode Psychosis Unmedicated with Antipsychotics; A Randomised Controlled Pilot Study. Journal of Psychopharmacology In Press https://doi.org/10.1177/0269881120922967
Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(5):e204693. https://doi.org/10.1001/jamanetworkopen.2020.4693
Applying economic models to estimate local economic benefits of improved coverage of early intervention for psychosis.
Early Intervention in Psychiatry 2019;13:1426-2430 https://doi.org/10.1111/eip.12787
Tamoxifen For Bipolar Disorder: Systematic Review And Meta-Analysis. Journal of Psychopharmacology 2019;33:177-184 https://doi.org/10.1177/0269881118822167
The Computerised Life Events and Assessment Record (CLEAR) online measure of life events: reliability, validity and association with depression.
JMIR Mental Health 2019-01 https://doi.org/10.2196/10675
Timing of onset of lithium relapse prevention in bipolar disorder: evidence from randomised trials
British Journal of Psychiatry 2018-11 https://doi.org/10.1192/bjp.2018.177
Language bias and comprehensive meta-analysis of folate for unipolar depression. Journal of Psychopharmacology 2018-10 https://doi.org/10.1177/0269881118788823
Is there rebound psychosis on withdrawal of antipsychotic medication in schizophrenia?Schizophrenia Research 2018-06 https://doi.org/10.1016/j.schres.2018.06.008
Who needs AESOP? Predicting long-term readmission rates from routine Early Intervention team discharge information Early Intervention in Psychiatry 2018-04 https://doi.org/10.1111/eip.12413
The CIRCuiTS Study (Implementation of Cognitive Remediation in Early Intervention Services): Protocol for a Randomised Controlled Trial
Trials 2018-03 https://doi.org/10.1186/s13063-018-2553-3
Glutamatergic Hypofunction in Medication-Free Major Depression: Secondary Effects of Affective Diagnosis and Relationship to Peripheral Glutaminase
Journal of Affective Disorders 2018-02 https://doi.org/10.1016/j.jad.2018.02.059
The Camden & Islington Research Database: Using electronic mental health records for research
PLOS One 2018-01 https://doi.org/10.1371/journal.pone.0190703