Research groups
William Sproviero
PhD
Oxford-Janssen Human Genomics Fellow
- Bioinformatician
Genetics of Dementia
I am part of the informatics team working on dementia and Alzheimer's Disease in the Translational Neuroscience and Dementia Research Group. I am a bioinformatician and a geneticist, and my main focus is to use large genetic datasets to better understanding the impact of genetic variants on Dementia onset and disease heterogeneity across patients. This requires the use of both classical common and rare genome-wide analyses, as well as, the application of more advanced machine learning methodologies, able to capture phenotypic and genetic differences in the same population cohort.
Recent publications
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Integrating the environmental and genetic architectures of aging and mortality.
Journal article
Argentieri MA. et al, (2025), Nat Med, 31, 1016 - 1025
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Genome-wide association neural networks identify genes linked to family history of Alzheimer's disease.
Journal article
Ghose U. et al, (2024), Brief Bioinform, 26
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Describing the effects of iron dyshomeostasis on cognitive function and dementia in UK Biobank
Journal article
Winchester LM. et al, (2023), Alzheimer's & Dementia, 19
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Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
Journal article
Amin N. et al, (2023), JAMA Psychiatry, 80, 597 - 609
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Integrating the environmental and genetic architectures of mortality and aging
Preprint
Argentieri A. et al, (2023)