Effect of moderate weight loss on prolactin secretion in normal female volunteers.
Anderson IM., Crook WS., Gartside SE., Parry-Billings M., Newsholme EA., Cowen PJ.
Sleep-related prolactin secretion and prolactin responses to the infusion of low doses of the dopamine antagonist, metoclopramide, and thyrotropin-releasing hormone were measured in 11 female volunteers before and after undertaking a diet in which they lost a mean of 3.1 kg in weight in 3 weeks. No effect of weight loss on these measures was found, but there was a significant, although modest, reduction in fasting plasma tryptophan concentration without any change in the concentration of competing amino acids.