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Oloyede and colleagues advocate for updating haematological monitoring requirements for clozapine, arguing that current protocols overestimate the risk of clozapine-induced agranulocytosis. Their research suggests that stringent monitoring may unnecessarily limit access to clozapine, a crucial treatment for resistant schizophrenia. The editorial supports calls for international consensus to carefully weigh the pros and cons of relaxing monitoring guidelines while ensuring comprehensive care for patients.

Original publication

DOI

10.1192/bjp.2024.150

Type

Journal article

Journal

Br J Psychiatry

Publication Date

03/10/2024

Pages

1 - 3

Keywords

Treatment-resistant schizophrenia, agranulocytosis, clozapine, haematological monitoring, pharmacovigilance